St. John's Wort vs Wellbutrin
Did you mean taking both St. John's Wort and Wellbutrin?
St. John's Wort
St. John's Wort is an alternative medication.
Wellbutrin is an antidepressant medication.
December 30, 1985
Number of discussions around the web Number of discussions + -
Side Effects and Concerns
Pregnancy Category (FDA) OpenClose all pregnancy categories
Adequate and well-controllted studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use of the drug in pregnant women clearly outweigh potential benefits.
FDA has not classified the drug.
Before taking Wellbutrin during pregnancy, consult your doctor or pharmacists to weigh the risks and benefits.
There may be a negative interaction between St. John's Wort and alcohol.
There may be a negative interaction between Wellbutrin and alcohol.
Method of use
Oral Drops, Pill
Capsule: 150 mg, 300 mg, 450 mg, 600 mg, 1000 mg
Tablet: 300 mg, 450 mg
Drops: 25 mg/mL
Tablet: 75 mg, 100 mg
No Food Instructions
No Food Instructions
St. John's Wort
Interaction between St. John's Wort and Wellbutrin: Undetermined interaction. Always consult your doctor before taking these medications together. Do not stop taking the medications without a physician's advice.
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Wellbutrin v. St. John's Wort
I suffered from extreme sadness and was prescribed Wellbutrin generic years ago. The side effects were difficult but it was a trade I was willing to take until my pharmacy changed generic manufacturers. The new one was like taking a sugar pill -- back to sadness and crying for no reason. I swapped to the name brand and it worked great until GSK sold the 300XL to Valeant out of Canada. I tried the SL that GSK still manufactures, but the side effects were severe tinnitus and vertigo, as well as some sadness returning. I finally stopped taking it and replaced it with 300 mg. St. John's Wort 3 x day and 5HTP 100 mg 2x day. I cannot tell you when I have been SO happy! The vertigo and tinnitus are gone, but most importantly, I have my joy back -- better than it has been since before I my depression began over 12 years ago. I made the change 2 months ago and I cannot recommend St. John's Wort & 5HTP combo enough!
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