Last Update November 14, 2015
Method of use: Pill
Prescribing mode: Rx
Satisfaction Score
5 1 338
Slightly Satisfied
based on 338 conversation around the web
Share your experience
Share your experience
Last Update November 14, 2015
Satisfaction Score
Slightly Satisfied
Share your experience
Share your experience
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What people say about Osphena

Concern level
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Share your experience
Positive 33 "I was previously taking Osphena for vaginal dryness - with good but not great results. I have been on Duavee... "Read more positive discussions
Negative 30 "I was previously taking Osphena for vaginal dryness - with good but not great results. I have been on Duavee... "Read more negative discussions
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We found 338 discussions
why would my insurance reject Osphena?
I'm 66 have tried Premarin and Estrace without any improvement. My doctor gave me about 20 of the Osphena pills and in that short time I was very happy (the dryness is so bad it feels like sticky fly paper. Cigna Health Srings will not cover it although the doctor prescribed it. I'm retired and the cost is to high for me without help.
June 24, 2015
I finally got mine to cover it but they only covered like $20. Go to the osphena website and you can get a coupon from the manufacturer with 6 months of savings. I used it and my cost was going to be $170 but with coupon it was $75. Much better. Makes me so mad that insurance companies can say whether we need a prescription that our DOCTOR prescribed. Grrr!

Love the Oshena, it really helped with the vaginal dryness & made having sex possible again. My doctor gave me samples as well as coupons to use if I wanted to get refills but the coupons can't put a dent in the cost! Because my insurance doesn't cover this, I would be paying $264.00 for a 30 ay supply & $578.00 for a 90 supply!!! Guess that saying "too good to be true" is true! :(

Have been taking for 2 1/2 months. No improvement with regard to discomfort. Am still having side-effects (hot flashes, sweating, leg cramps, nervousness and anxiety.) The doctor told me it takes time to work. Considering stopping Osphena.
February 6, 2015
I've been on Osphena for about 8 months and it's not helped with intercourse pain (burning). Plus I have hot flashes and sweating all day! It's worse than going through menopause as I had only a couple of episodes the. I'm going to stop the Osphena but wonder what to try next?

Blister Pack
I just started taking Osphena. I can't say I've noticed any difference yet as far as the pain goes.

One thing that really annoys me about Osphena has nothing at all to do with the pills itself. It is the fact that I have arthritis in my thumbs and I can't push the pills through the cardboard. I find it totally unacceptable that a company who makes a product for older women doesn't take into consideration the fact that many of us have arthritic hands, or that we just don't want to go through the hassle of pills in blister packs. Put them in a damn bottle!!!
Debi Sue
March 6, 2015
I guess this answers my question of why I'm having so many hot flashes these days! And, when I weighed in at the doctor's office the other day, I couldn't believe I had gained weight. I'm stopping Osphena as of right now!
February 17, 2015
the refill I picked up today (from CVS) is in a bottle! Yay!
January 25, 2015
Yes, I agree...the drug is expensive, and the blister packs are a pain!
December 1, 2014
The cost is one issue, $$$++++, but the blister-pak is a deal breaker for me. This drug is not worth the trouble.
November 10, 2014
YESSSSS! I totally HATE the blister packs! My husband has to poke all my pills out each month and transfer them to an empty bottle.
November 2, 2014
Yep. So irritating. Have broken nails trying to force the stupid pills through the back. Some man designed it I bed haha
Carolina Girl
October 17, 2014
As I was saying, I traced back to when I started taking Osphena, and guess what? It was exactly when I started gaining weight. Now I am trying to lose the 8 pounds again. There is no mention of this as a side effect on any of the sites I have checked. Anyone else out having the same problem?
Carolina Girl
October 17, 2014
So good to know I'm not the only one with the packaging problem. I have to use scissors and cut around each tablet to get the darn thing out. I usually do this when I get my script and transfer them to a MEDICINE BOTTLE THAT IS NOT CHILD PROOF!!!!!!!!!!!!! It's almost enough to make me stop taking the medication!! Not only this but I had been dieting before I started taking OSPHENA and had gotten to my goal weight. Then I started gaining weight because I seem to be always hungry. I traced back
August 23, 2014
I absolutely agree 100 % !!!!!!!!!!

urethral atrophy
I have been diagnosed with urethral atrophy and been prescribed Estrace cream for 15 years. It has worked fairly well but not perfectly. I was wondering if Osphena would be of help for my condition?
March 9, 2015
I could not agree with this post anymore! Amen!!!!!!!!!!!!!

ain but both persisted. I took osphena at full dose for 3 m...
" forgot to say: I cut the dosage in half hoping to lessen the symptoms of both the sweats and tendon pain but both persisted. I took osphena at full dose for 3 ...has continued… I REGRET having... "
July 27, 2015

burnI have only been on Osphena for two days and I'm in a...
" Started Osphena....Burn burn burn I have only been on Osphena for two days and I'm ...I \"think\" it must be the Osphena. ???? Only because it's different. ...NEED someone to talk to about Osphena. Is... "

cause sleep issues?I have just started osphena, and w...
" Does osphena cause sleep issues? I have just started osphena, and wake, feeling as if ...night. I also a having hot flashes... "

aginal dryness. Been on Osphena for 3 weeks and noticed a...
" Anyone experience vaginal discharge while taking Osphena. I had a total hysterectomy ...now with vaginal dryness. Been on Osphena for 3 weeks and... "

anyone taken Osphena with psychiatric meds? I am bipolar...
" Has anyone taken Osphena with psychiatric meds? I am bipolar and have been doing ...will be issues with adding Osphena however, I am still... "

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