Melatonin vs Silenor

Melatonin
(OTC)
Silenor
(Rx)
Melatonin is a sleep medication and an alternative medication.
Silenor is a sleep medication.
Satisfaction Score
?
3.6
Moderately Satisfied
Satisfaction Score
?
3.6
Moderately Satisfied
Helpfulness
for Insomnia
4.2
Concern level
1.8
Approval Date
+ -
Not Available
March 17, 2010
Number of discussions around the web Number of discussions + -
271,837 Discussions
646 Discussions
Taken For
+ -
Condition
Number of posts
#1 for Insomnia
#3 for Cancer
#4 for Autism
Melatonin is approved for Insomnia and is mostly mentioned together with this indication.
Condition
Number of posts
#1 for Insomnia
#2 for Depression
#3 for Anxiety
Silenor is prescribed for Insomnia, Depression and Anxiety and is mostly mentioned together with these indications.
Side Effects and Concerns
+ -
Mel
Grogginess
3
Drowsiness
3
Withdrawal Symptoms
3
Headaches
2
Nightmares
2
Vivid Dreams
2
Restlessness
1
Hangover
1
Weight Gain
1
Weight Loss
1
Sil
Grogginess
6
Hangover
5
Withdrawal Symptoms
5
Weight Gain
4
Weakness
2
Hallucinations
2
Irritability
2
Headaches
2
Sleep Walking
2
RLS
1
Compare concerns
By:
Melatonin
Mel
Silenor
Sil
Grogginess
Mel
Sil
3
6
Drowsiness
Mel
Sil
3
0
Withdrawal Symptoms
Mel
Sil
3
5
Headaches
Mel
Sil
2
2
Nightmares
Mel
Sil
2
0
Vivid Dreams
Mel
Sil
2
0
Restlessness
Mel
Sil
1
0
Hangover
Mel
Sil
1
5
Weight Gain
Mel
Sil
1
4
Weight Loss
Mel
Sil
1
0
Grogginess
Sil
Mel
6
3
Hangover
Sil
Mel
5
1
Withdrawal Symptoms
Sil
Mel
5
3
Weight Gain
Sil
Mel
4
1
Weakness
Sil
Mel
2
0
Hallucinations
Sil
Mel
2
0
Irritability
Sil
Mel
2
0
Headaches
Sil
Mel
2
2
Sleep Walking
Sil
Mel
2
0
RLS
Sil
Mel
1
0
Pregnancy Category (FDA) OpenClose all pregnancy categories
+ -
a b c d x n
Category A
Adequate and well-controllted studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
Category B
Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
Category C
Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Category D
There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Category X
Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use of the drug in pregnant women clearly outweigh potential benefits.
Category N
FDA has not classified the drug.
close
Not Available
C Category C
Before taking Silenor during pregnancy, consult your doctor or pharmacists to weigh the risks and benefits.
Alcohol warning
+ -
There may be a negative interaction between Silenor and alcohol.
Method of use
+ -
Lozenge, Oral Drops, Pill
Pill
Dosages
+ -
Tablet: 200 mcg, 300 mcg, 500 mcg, 500 mcg-20 mg-50 mg, 1 mg, 1.5 mg, 2.5 mg, 3 mg, 5 mg, 10 mg, 0.5-5 mg, 3-2 mg
Liquid: 2.5 mg/10 mL, 5 mg/15 mL, 1 mg/mL
Capsule: 5 mg, 10 mg
Drops: 1 mg/4 mL
Lozenge: 3 mg
Tablet: 3 mg, 6 mg
Food Instructions
+ -
No Food Instructions
No Food Instructions
Ingredients
+ -
Melatonin , Calcium Phosphate/Melatonin , Melatonin/Pyridoxine
Doxepin Hcl
Drug Interactions
+ -
Interaction between Melatonin and Silenor: Interaction not known, but may still exist. Always consult your doctor before taking these medications together. Do not stop taking the medications without a physician's advice.
Read more about:
Melatonin
Read more about:
Silenor
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The side effects featured here are based on those most frequently appearing in user posts on the Internet. The manufacturer's product labeling should always be consulted for a list of side effects most frequently appearing in patients during clinical studies. Talk to your doctor about which medications may be most appropriate for you.
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