Gabapentin vs Horizant

Gabapentin
(Rx)
Horizant
(Rx)
Gabapentin is an epilepsy medication and a nervous system medication.
Horizant is a nervous system medication.
Satisfaction Score
?
3.5
Moderately Satisfied
Satisfaction Score
?
3.4
Moderately Satisfied
Helpfulness
for RLS
3.4
Concern level
1.7
Approval Date
+ -
September 12, 2003
April 6, 2011
Number of discussions around the web Number of discussions + -
135,950 Discussions
883 Discussions
Taken For
+ -
Condition
Number of posts
#1 for Nerve Pain
#2 for Anxiety
#4 for Depression
#5 for Fibromyalgia
#6 for Neuropathy
#7 for Seizures
#8 for Numbness
#9 for Headaches
#10 for RLS
#11 for Migraines
#12 for Epilepsy
#13 for Tingling
#14 for Chronic Pain
#15 for Back Pain
#17 for Leg Pain
#18 for Shingles
#19 for Hot Flashes
#20 for Sciatica
Gabapentin is prescribed for Nerve Pain, Fibromyalgia, Neuropathy, Seizures and Numbness and is mostly mentioned together with these indications. Our data suggest that it is taken for Anxiety, Depression, RLS, Withdrawal Symptoms and Headaches, although it is not approved for these conditions.
Condition
Number of posts
#1 for RLS
#2 for Nerve Pain
#3 for Seizures
#4 for Neuropathy
#5 for Epilepsy
#7 for Chronic Pain
Horizant is prescribed for RLS and is mostly mentioned together with this indication.
Side Effects and Concerns
+ -
Gab
Dizziness
4
Drowsiness
3
Nausea
3
Weight Loss
1
Euphoria
1
Dry Mouth
1
Grogginess
1
Mood Swings
1
Hallucinations
1
Suicidal behavior
1
Hor
Withdrawal Symptoms
9
Drowsiness
6
Depression
6
Weight Gain
5
Nausea
4
Dizziness
3
Addiction
3
Migraines
3
Sleep Disorders
3
Restlessness
3
Compare concerns
By:
Gabapentin
Gab
Horizant
Hor
Dizziness
Gab
Hor
4
3
Drowsiness
Gab
Hor
3
6
Nausea
Gab
Hor
3
4
Weight Loss
Gab
Hor
1
0
Euphoria
Gab
Hor
1
0
Dry Mouth
Gab
Hor
1
0
Grogginess
Gab
Hor
1
0
Mood Swings
Gab
Hor
1
0
Hallucinations
Gab
Hor
1
0
Suicidal behavior
Gab
Hor
1
0
Withdrawal Symptoms
Hor
Gab
9
0
Drowsiness
Hor
Gab
6
3
Depression
Hor
Gab
6
0
Weight Gain
Hor
Gab
5
0
Nausea
Hor
Gab
4
3
Dizziness
Hor
Gab
3
4
Addiction
Hor
Gab
3
0
Migraines
Hor
Gab
3
0
Sleep Disorders
Hor
Gab
3
0
Restlessness
Hor
Gab
3
0
Pregnancy Category (FDA) OpenClose all pregnancy categories
+ -
a b c d x n
Category A
Adequate and well-controllted studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
Category B
Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
Category C
Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Category D
There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Category X
Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use of the drug in pregnant women clearly outweigh potential benefits.
Category N
FDA has not classified the drug.
close
C Category C
Before taking Gabapentin during pregnancy, consult your doctor or pharmacists to weigh the risks and benefits.
C Category C
Before taking Horizant during pregnancy, consult your doctor or pharmacists to weigh the risks and benefits.
Alcohol warning
+ -
There may be a negative interaction between Gabapentin and alcohol.
There may be a negative interaction between Horizant and alcohol.
Method of use
+ -
Pill
Pill
Dosages
+ -
Tablet: 300 mg (9)- 600 mg (69), 100 mg, 300 mg, 400 mg, 600 mg, 800 mg
Capsule: 100 mg, 300 mg, 400 mg
Solution: 250 mg/5 mL, 250 mg/5 mL (5 mL), 300 mg/6 mL (6 mL)
Suspension: 25 mg/mL
Tablet: 300 mg, 600 mg
Food Instructions
+ -
No Food Instructions
No Food Instructions
Ingredients
+ -
Gabapentin
Gabapentin enacarbil
Drug Interactions
+ -
Interaction between Gabapentin and Horizant: Interaction not known, but may still exist. Always consult your doctor before taking these medications together. Do not stop taking the medications without a physician's advice.
Read more about:
Gabapentin
Read more about:
Horizant
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We found 374 discussions
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| RogueKitten
I have a traumatic spinal cord injury with a baclofen pump. My legs ache and I have increasing periferal neuropathy. I am 4.5 years post injury. A pain management specialist switched me from 1200 mg gabapentin to 1200 mg horizant two months ago. Withdraw from gabapentin is painful and results in increased cramping and rls -like symptoms (although I twitch and spasm all the time, this is different). Horizant seems more effective and I have less pain when I wake up, probably because horizant is time release and gabapentin is not.

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Gabapetin versus Horizant
| Ricardo
I have been taking Pramipexole for several years to help my RLS and to help my sleep problem.
The RLS continued to worsen but I continued to take it as it seemed to help me sleep.
My doctor put me on Horizant but that did no good so I quit taking it but continued the Pramipexole.
A few months ago another doctor prescribed Gabapetin for my RLS and overnight my RLS all but disappeared.
A couple of days after that miracle I forgot to take the Pramipexole and the RLS came back.
When I took it again, the RLS stopped.
I then experimented and twice did not take the Pramipexole and each time the RLS returned.
It is clear to me that as long as I take the Pramipexole and Gabapetin in conjunction my RLS is a thing of the past.
If I take either by itself, the RLS returns.
Now comes the confusing part:
I have learned that Gabapetin and Horizant are the same thing, with different names.
If that is the case why does the Gabapetin solve my problem when the Horizant did not?
D
August 14, 2014
does anyone else get the night-sweats from Horizant?
May 24, 2014
Maybe you needed a higher dose. I started at 100 my a day if Gabapentin for RLS. Now I am taking 300 me 2xs a day. Works for the most part but do still have bad nights. Good luck.

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The side effects featured here are based on those most frequently appearing in user posts on the Internet. The manufacturer's product labeling should always be consulted for a list of side effects most frequently appearing in patients during clinical studies. Talk to your doctor about which medications may be most appropriate for you.
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