Enbrel vs Simponi

Enbrel
(Rx)
Simponi
(Rx)
Enbrel is an arthritis medication.
Simponi is an arthritis medication.
Satisfaction Score
?
3.5
Moderately Satisfied
Satisfaction Score
?
3.4
Moderately Satisfied
Helpfulness
for RA
3.7
Concern level
1.8
Helpfulness
for RA
3.8
Concern level
1.4
Approval Date
+ -
November 2, 1998
April 24, 2009
Number of discussions around the web Number of discussions + -
122,750 Discussions
8,225 Discussions
Taken For
+ -
Condition
Number of posts
Enbrel is prescribed for RA, Psoriasis, Psoriatic Arthritis and Arthritis and is mostly mentioned together with these indications.
Condition
Number of posts
Simponi is prescribed for RA, Psoriatic Arthritis, Ulcerative Colitis, Psoriasis and Arthritis and is mostly mentioned together with these indications.
Side Effects and Concerns
+ -
Enb
Itching
8
Nausea
4
Rash
4
Weight Gain
3
Common Cold
3
Bruise
3
Hair Loss
2
Fever
2
Lymphoma
2
Sinus Infections
2
Sim
Nausea
4
Rash
3
Hair Loss
3
Weight Gain
2
Sinus Infections
2
Bruise
1
Lymphoma
1
Injection Site Reactions
1
Cough
1
Diabetes
1
Compare concerns
By:
Enbrel
Enb
Simponi
Sim
Itching
Enb
Sim
8
0
Nausea
Enb
Sim
4
4
Rash
Enb
Sim
4
3
Weight Gain
Enb
Sim
3
2
Common Cold
Enb
Sim
3
0
Bruise
Enb
Sim
3
1
Hair Loss
Enb
Sim
2
3
Fever
Enb
Sim
2
0
Lymphoma
Enb
Sim
2
1
Sinus Infections
Enb
Sim
2
2
Nausea
Sim
Enb
4
4
Rash
Sim
Enb
3
4
Hair Loss
Sim
Enb
3
2
Weight Gain
Sim
Enb
2
3
Sinus Infections
Sim
Enb
2
2
Bruise
Sim
Enb
1
3
Lymphoma
Sim
Enb
1
2
Injection Site Reactions
Sim
Enb
1
0
Cough
Sim
Enb
1
0
Diabetes
Sim
Enb
1
0
Pregnancy Category (FDA) OpenClose all pregnancy categories
+ -
a b c d x n
Category A
Adequate and well-controllted studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
Category B
Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
Category C
Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Category D
There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Category X
Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use of the drug in pregnant women clearly outweigh potential benefits.
Category N
FDA has not classified the drug.
close
B Category B
Before taking Enbrel during pregnancy, consult your doctor or pharmacists to weigh the risks and benefits.
B Category B
Before taking Simponi during pregnancy, consult your doctor or pharmacists to weigh the risks and benefits.
Alcohol warning
+ -
There may be a negative interaction between Enbrel and alcohol.
There may be a negative interaction between Simponi and alcohol.
Method of use
+ -
Injection
Injection
Dosages
+ -
Syringe: 25 mg/0.5mL (0.51), 50 mg/mL (0.98 mL)
Injector: 50 mg/mL (0.98 mL)
Solution: 25 mg (1 mL)
Injector: 50 mg/0.5 mL, 100 mg/mL
Syringe: 50 mg/0.5 mL, 100 mg/mL
Solution: 12.5 mg/mL
Food Instructions
+ -
No Food Instructions
No Food Instructions
Ingredients
+ -
Etanercept
Golimumab
Drug Interactions
+ -
Interaction between Enbrel and Simponi: Interaction not known, but may still exist. Always consult your doctor before taking these medications together. Do not stop taking the medications without a physician's advice.
Read more about:
Enbrel
Read more about:
Simponi
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We found 1,496 discussions
?
golimimab
| Margaret8
My dose of golimumab does not seem to have been effective this month. Why?

?
simponi,
| shirley been on simponi and methotrexate for 1yr.
been on simponi and methotrexate for1 yr. takes away most of pain butstill very very fatigued also after 3 weeks it gradually stops working until next shot which is every 30 days.think I will go to Enbrel I've been reading it takes away a lot of the ra fatigue the fatigue is as bad as the pain, no quality of life

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The side effects featured here are based on those most frequently appearing in user posts on the Internet. The manufacturer's product labeling should always be consulted for a list of side effects most frequently appearing in patients during clinical studies. Talk to your doctor about which medications may be most appropriate for you.
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