Cymbalta vs Pristiq

Cymbalta
(Rx)
Pristiq
(Rx)
Cymbalta is a nervous system medication and an antidepressant medication.
Pristiq is an antidepressant medication.
Satisfaction Score
?
3.4
Moderately Satisfied
Satisfaction Score
?
3.4
Moderately Satisfied
Helpfulness
for Depression
3.1
Concern level
1.8
Helpfulness
for Depression
2.5
Concern level
2.0
Approval Date
+ -
August 3, 2004
February 29, 2008
Number of discussions around the web Number of discussions + -
193,803 Discussions
34,613 Discussions
Taken For
+ -
Condition
Number of posts
#1 for Depression
#2 for Anxiety
#3 for Fibromyalgia
#4 for Nerve Pain
#5 for Headaches
#7 for Migraines
#8 for Neuropathy
#9 for GAD
#10 for OCD
#12 for Back Pain
Cymbalta is prescribed for Depression, Anxiety and Fibromyalgia and is mostly mentioned together with these indications.
Condition
Number of posts
#1 for Depression
#2 for Anxiety
#4 for Panic
#6 for GAD
Pristiq is prescribed for Depression and is mostly mentioned together with this indication. In addition, our data suggest that it is taken for Anxiety, although it is not approved for this condition.
Side Effects and Concerns
+ -
Cym
Withdrawal Symptoms
8
Weight Gain
5
Nausea
3
Dizziness
3
Head Zaps
2
Sexual Dysfunction
1
Drowsiness
1
Suicidal behavior
1
Seizures
1
Suicidal Thoughts
1
Pri
Withdrawal Symptoms
10
Weight Gain
6
Nausea
5
Dizziness
3
Head Zaps
2
Sexual Dysfunction
2
Serotonin Syndrome
2
Drowsiness
1
Suicidal behavior
1
Decreased Libido
1
Compare concerns
By:
Cymbalta
Cym
Pristiq
Pri
Withdrawal Symptoms
Cym
Pri
8
10
Weight Gain
Cym
Pri
5
6
Nausea
Cym
Pri
3
5
Dizziness
Cym
Pri
3
3
Head Zaps
Cym
Pri
2
2
Sexual Dysfunction
Cym
Pri
1
2
Drowsiness
Cym
Pri
1
1
Suicidal behavior
Cym
Pri
1
1
Seizures
Cym
Pri
1
0
Suicidal Thoughts
Cym
Pri
1
0
Withdrawal Symptoms
Pri
Cym
10
8
Weight Gain
Pri
Cym
6
5
Nausea
Pri
Cym
5
3
Dizziness
Pri
Cym
3
3
Head Zaps
Pri
Cym
2
2
Sexual Dysfunction
Pri
Cym
2
1
Serotonin Syndrome
Pri
Cym
2
0
Drowsiness
Pri
Cym
1
1
Suicidal behavior
Pri
Cym
1
1
Decreased Libido
Pri
Cym
1
0
Pregnancy Category (FDA) OpenClose all pregnancy categories
+ -
a b c d x n
Category A
Adequate and well-controllted studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
Category B
Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
Category C
Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Category D
There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Category X
Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use of the drug in pregnant women clearly outweigh potential benefits.
Category N
FDA has not classified the drug.
close
C Category C
Before taking Cymbalta during pregnancy, consult your doctor or pharmacists to weigh the risks and benefits.
C Category C
Before taking Pristiq during pregnancy, consult your doctor or pharmacists to weigh the risks and benefits.
Alcohol warning
+ -
There may be a negative interaction between Cymbalta and alcohol.
There may be a negative interaction between Pristiq and alcohol.
Method of use
+ -
Pill
Pill
Dosages
+ -
Capsule: 20 mg, 30 mg, 60 mg
Tablet: 25 mg, 50 mg, 100 mg
Food Instructions
+ -
No Food Instructions
No Food Instructions
Ingredients
+ -
Duloxetine Hcl
Desvenlafaxine
Drug Interactions
+ -
Interaction between Cymbalta and Pristiq: Interaction not known, but may still exist. Always consult your doctor before taking these medications together. Do not stop taking the medications without a physician's advice.
Read more about:
Cymbalta
Read more about:
Pristiq
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We found 3,555 discussions
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Cymbalta and Prestiq
| Songstylist
I use both Cymbalta and Prestiq for about 4 years now. It is the best combination of meds that works for me. I maxed out on Paxil, and Effexor when my doctor put me on Cymbalta 30 then 60 then 90. Cymbalta 90mg got rid of all of my symptoms of depression until about 4 years ago and it raised it's ugly head again. He then added Pristiq 50mg and then we upped it to 100mg as my depression was still not effectively controlled. I have done wonderfully, no need to change meds. Until my part D medicare decided it would no longer pay for the Pristiq. So I was put on Celexa 10mg, then increased the next month to 20mg. It has become obvious that not only does Celexa not work for me, I have had a 5 pound weight gain, find myself craving carbs, sleeping too much, no energy for activities, chewing my nails and cuticles. I called my MD's office yesterday and I have been switched back to Pristiq at 50mg to start. I am experiencing nausea but know that will pass in about a week. If your anti-depressant isn't working, please talk to your MD about Pristiq (and Cymbalta). . I live with chronic pain and cannot imagine what life would be without the Cymbalta for both pain and depression. Hope this helps someone out there. :)
cassie r
April 6, 2015
Thank you for your experience. ..I've been on wellbutrin for 2 years and Zoloft for 8 yrs just dx with fibromyalgia and been dealing with IBS for over a year. .gained 25 lbs cause in so much pain & then depression...vicious cycle..spinal stenosis anxiety all connected...just need to find something to stop the cycle so I can function and get some weight off...along with chronic COPD & bacterial pneumonia...I exercise when I feel somewhat ok..but then next day totally wiped out...I'm interested i

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The side effects featured here are based on those most frequently appearing in user posts on the Internet. The manufacturer's product labeling should always be consulted for a list of side effects most frequently appearing in patients during clinical studies. Talk to your doctor about which medications may be most appropriate for you.
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