Benadryl vs Promethazine

Benadryl
(OTC)
Promethazine
(Rx)
Benadryl is a skin medication and a systemic antihistamine.
Promethazine is a systemic antihistamine and a nausea & vomiting medication.
Satisfaction Score
?
3.7
Moderately Satisfied
Satisfaction Score
?
4.2
Very Satisfied
Helpfulness
for Nausea
2.6
Concern level
1.4
Helpfulness
for Nausea
3.0
Concern level
1.2
Approval Date
+ -
March 4, 1946
Not Available
Number of discussions around the web Number of discussions + -
372,264 Discussions
20,142 Discussions
Taken For
+ -
Condition
Number of posts
#1 for Allergy
#2 for Itching
#3 for Hives
#4 for Insomnia
#5 for Rash
#6 for Swelling
#7 for Anxiety
#8 for Nausea
#9 for Headaches
#10 for Cough
#11 for Vomiting
#13 for Sleep Disorders
#14 for Sneezing
Benadryl is approved for Allergy, Itching, Hives, Rash, Insomnia and Swelling and is mostly mentioned together with these indications.
Condition
Number of posts
#1 for Nausea
#2 for Pain
#3 for Vomiting
#4 for Sedation
#5 for Allergy
#6 for Itching
#7 for Sedative
#10 for Migraines
Promethazine is prescribed for Nausea, Pain, Vomiting and Sedation and is mostly mentioned together with these indications.
Side Effects and Concerns
+ -
Ben
Dry Mouth
1
Euphoria
1
Delirium
1
Suicide
1
Blood Clots
1
Stretch Marks
1
Blurred Vision
1
Dry Eyes
1
Candida
1
Weird Dreams
1
Pro
Euphoria
7
Dry Mouth
3
Delirium
2
Respiratory Depression
1
Blurred Vision
1
High Blood Pressure
1
Mood Swings
1
Mania
1
Bleeding
1
Hypomania
1
Compare concerns
By:
Benadryl
Ben
Promethazine
Pro
Dry Mouth
Ben
Pro
1
3
Euphoria
Ben
Pro
1
7
Delirium
Ben
Pro
1
2
Suicide
Ben
Pro
1
0
Blood Clots
Ben
Pro
1
0
Stretch Marks
Ben
Pro
1
0
Blurred Vision
Ben
Pro
1
1
Dry Eyes
Ben
Pro
1
0
Candida
Ben
Pro
1
0
Weird Dreams
Ben
Pro
1
0
Euphoria
Pro
Ben
7
1
Dry Mouth
Pro
Ben
3
1
Delirium
Pro
Ben
2
1
Respiratory Depression
Pro
Ben
1
0
Blurred Vision
Pro
Ben
1
1
High Blood Pressure
Pro
Ben
1
0
Mood Swings
Pro
Ben
1
0
Mania
Pro
Ben
1
0
Bleeding
Pro
Ben
1
0
Hypomania
Pro
Ben
1
0
Pregnancy Category (FDA) OpenClose all pregnancy categories
+ -
a b c d x n
Category A
Adequate and well-controllted studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
Category B
Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
Category C
Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Category D
There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Category X
Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use of the drug in pregnant women clearly outweigh potential benefits.
Category N
FDA has not classified the drug.
close
B Category B
Before taking Benadryl during pregnancy, consult your doctor or pharmacists to weigh the risks and benefits.
C Category C
Before taking Promethazine during pregnancy, consult your doctor or pharmacists to weigh the risks and benefits.
Alcohol warning
+ -
There may be a negative interaction between Benadryl and alcohol.
There may be a negative interaction between Promethazine and alcohol.
Method of use
+ -
Injection, Ointment, Pill
Injection, Pill, Syrup
Dosages
+ -
Capsule: 25 mg, 50 mg
Cream: 1%, 1%-0.1%
Liquid: 6.25 mg/5 mL, 12.5 mg/5 mL
Solution: 10 mg/mL, 50 mg/mL
Elixir: 12.5 mg/5 mL
Syringe: 50 mg/mL
Tablet: 25 mg
Suppository: 12.5 mg, 25 mg, 50 mg
Tablet: 12.5 mg, 25 mg, 50 mg
Solution: 25 mg/mL, 50 mg/mL
Syringe: 25 mg/mL, 50 mg/mL
Syrup: 6.25 mg/5 mL, 25 mg/5 mL
Food Instructions
+ -
No Food Instructions
No Food Instructions
Ingredients
+ -
Diphenhydramine Hcl , Diphenhydramine Hcl/Zinc Acetate
Promethazine Hcl
Drug Interactions
+ -
Interaction between Benadryl and Promethazine: Interaction not known, but may still exist. Always consult your doctor before taking these medications together. Do not stop taking the medications without a physician's advice.
Read more about:
Benadryl
Read more about:
Promethazine
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Treato does not review third-party posts for accuracy of any kind, including for medical diagnosis or treatments, or events in general. Treato does not provide medical advice, diagnosis or treatment. Usage of the website does not substitute professional medical advice.
The side effects featured here are based on those most frequently appearing in user posts on the Internet. The manufacturer's product labeling should always be consulted for a list of side effects most frequently appearing in patients during clinical studies. Talk to your doctor about which medications may be most appropriate for you.
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