Baclofen vs Tizanidine

Baclofen
(Rx)
Tizanidine
(Rx)
Baclofen is a muscle relaxant.
Tizanidine is a muscle relaxant.
Satisfaction Score
?
3.4
Moderately Satisfied
Satisfaction Score
?
4.0
Very Satisfied
Helpfulness
for Spasms
2.5
Concern level
1.6
Helpfulness
for Spasms
2.6
Concern level
1.6
Approval Date
+ -
July 21, 1988
Not Available
Number of discussions around the web Number of discussions + -
66,315 Discussions
5,343 Discussions
Taken For
+ -
Condition
Number of posts
#1 for Spasms
#2 for Spasticity
#3 for Anxiety
#4 for Stiffness
#5 for Nerve Pain
#6 for Cramping
#7 for Leg Cramps
Baclofen is prescribed for Spasticity, Stiffness, Nerve Pain and Cramping and is mostly mentioned together with these indications. In addition, our data suggest that some patients take it for Anxiety, although this is not an approved use.
Condition
Number of posts
#1 for Spasms
#2 for Spasticity
#3 for Fibromyalgia
Tizanidine is prescribed for Spasticity and Fibromyalgia and is mostly mentioned together with these indications.
Side Effects and Concerns
+ -
Bac
Withdrawal Symptoms
9
Depression
6
Drowsiness
4
Nausea
3
Euphoria
1
Vomiting
1
Hallucinations
1
Itching
1
Dry Mouth
1
Stroke
1
Tiz
Drowsiness
8
Withdrawal Symptoms
6
Nausea
5
Dry Mouth
4
Low Blood Pressure
2
Hallucinations
2
Fainting
2
High Blood Pressure
1
UTI
1
Euphoria
1
Compare concerns
By:
Baclofen
Bac
Tizanidine
Tiz
Withdrawal Symptoms
Bac
Tiz
9
6
Depression
Bac
Tiz
6
0
Drowsiness
Bac
Tiz
4
8
Nausea
Bac
Tiz
3
5
Euphoria
Bac
Tiz
1
1
Vomiting
Bac
Tiz
1
0
Hallucinations
Bac
Tiz
1
2
Itching
Bac
Tiz
1
0
Dry Mouth
Bac
Tiz
1
4
Stroke
Bac
Tiz
1
0
Drowsiness
Tiz
Bac
8
4
Withdrawal Symptoms
Tiz
Bac
6
9
Nausea
Tiz
Bac
5
3
Dry Mouth
Tiz
Bac
4
1
Low Blood Pressure
Tiz
Bac
2
0
Hallucinations
Tiz
Bac
2
1
Fainting
Tiz
Bac
2
0
High Blood Pressure
Tiz
Bac
1
0
UTI
Tiz
Bac
1
0
Euphoria
Tiz
Bac
1
1
Pregnancy Category (FDA) OpenClose all pregnancy categories
+ -
a b c d x n
Category A
Adequate and well-controllted studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
Category B
Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
Category C
Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Category D
There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Category X
Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use of the drug in pregnant women clearly outweigh potential benefits.
Category N
FDA has not classified the drug.
close
C Category C
Before taking Baclofen during pregnancy, consult your doctor or pharmacists to weigh the risks and benefits.
C Category C
Before taking Tizanidine during pregnancy, consult your doctor or pharmacists to weigh the risks and benefits.
Alcohol warning
+ -
There may be a negative interaction between Baclofen and alcohol.
There may be a negative interaction between Tizanidine and alcohol.
Method of use
+ -
Pill
Pill
Dosages
+ -
Solution: 20000 mcg/20mL (1,000 mcg/mL), 40000 mcg/20mL (2,000 mcg/mL), 10000 mcg/20mL (500 mcg/mL), 50 mcg/mL, 500 mcg/mL, 2000 mcg/mL
Syringe: 20000 mcg/20mL (1,000 mcg/mL), 40000 mcg/20mL (2,000 mcg/mL), 10000 mcg/20mL (500 mcg/mL), 50 mcg/mL (1 mL)
Kit: 500 mcg/mL, 0.05 mg/mL
Tablet: 10 mg, 20 mg
Capsule: 2 mg, 4 mg, 6 mg
Tablet: 2 mg, 4 mg
Food Instructions
+ -
No Food Instructions
No Food Instructions
Ingredients
+ -
Baclofen
Tizanidine Hcl
Drug Interactions
+ -
Interaction between Baclofen and Tizanidine: Interaction not known, but may still exist. Always consult your doctor before taking these medications together. Do not stop taking the medications without a physician's advice.
Read more about:
Baclofen
Read more about:
Tizanidine
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The side effects featured here are based on those most frequently appearing in user posts on the Internet. The manufacturer's product labeling should always be consulted for a list of side effects most frequently appearing in patients during clinical studies. Talk to your doctor about which medications may be most appropriate for you.
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