Amitriptyline vs Lyrica
Did you mean taking both Amitriptyline and Lyrica?
Amitriptyline is an antidepressant medication.
Lyrica is a nervous system medication and an epilepsy medication.
December 30, 2004
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Amitriptyline is prescribed for Depression, Headaches, Insomnia and Weight Issues and is mostly mentioned together with these indications. Our data suggest that it is taken for Anxiety, Fibromyalgia and Nerve Pain, although it is not approved for these conditions. In addition, it is taken to prevent Migraines.
Side Effects and Concerns
Pregnancy Category (FDA) OpenClose all pregnancy categories
Adequate and well-controllted studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use of the drug in pregnant women clearly outweigh potential benefits.
FDA has not classified the drug.
Before taking Amitriptyline during pregnancy, consult your doctor or pharmacists to weigh the risks and benefits.
There may be a negative interaction between Amitriptyline and alcohol.
There may be a negative interaction between Lyrica and alcohol.
Method of use
Tablet: 10 mg, 25 mg, 50 mg, 75 mg, 100 mg, 150 mg
Solution: 10 mg/mL
Capsule: 25 mg, 50 mg, 75 mg, 100 mg, 150 mg, 200 mg, 225 mg, 300 mg
Solution: 20 mg/mL
No Food Instructions
No Food Instructions
Interaction between Amitriptyline and Lyrica: Interaction not known, but may still exist. Always consult your doctor before taking these medications together. Do not stop taking the medications without a physician's advice.
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