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Trazodone

Rx
/ 72,368 posts
Other Names: Desyrel   Oleptro   Molipaxin

Zoloft

Rx
/ 293,656 posts
Other Names: Sertraline   Lustral
Rating: 3.5 out of 5
Based on 72,368 patient discussions on healthcare websites and blogs
Learn more
Rating: 4 out of 5
Based on 293,656 patient discussions on healthcare websites and blogs
Learn more
Trazodone (also sold under the brand names Desyrel, Oleptro, Beneficat, Deprax, Desirel, Molipaxin, Thombran, Trazorel, Trialodine, Trittico, and Mesyrel) is an antidepressant of the serot... Read more on Wikipedia
Sertraline hydrochloride (brand names Zoloft and Lustral) is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. It was introduced to the market by Pfizer in 1991. Sertraline is primarily used to treat major depressi... Read more on Wikipedia
Concern level
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Help people by sharing experiences you've had with Trazodone or Zoloft - your story could impact others.
Treato My Voice
By David
September 24, 2014
David wrote
Zoloft- Unconscious and depressed. Low dose prescription for 1 year worked
Comment on this post
By Jeff F
September 8, 2014
Jeff F wrote
Trazodone - Leg cramps
Comment on this post
By Monk718
August 21, 2014
Monk718 wrote
Trazadone nightmares
I have had the exact same problem :(
moe  |  October 19, 2014
Comment on this post
By Jill Jes
August 7, 2014
Jill Jes wrote
Allergic Reaction to Trazadone
It ruined my life!!! I would she someone if I could
Lori  |  September 9, 2014
I took the pill for 45 days and felt like a zombie after two days. I got galactorrhea, complete sexual labido cut off, a vaginal discharge for 20 years now the symptoms don't stop. Oh and my hair quit growing on my legs and armpits. Dopamine helps. But gives me a headache. Stay away from anti depressants!!!
Lori  |  September 9, 2014
I didn't have this reaction. If fact, Trazodone has been very helpful for me for sleep with no side effects. I DID have exactly the same experience you are describing when I took my one and only Cymbalta pill for fibromyalgia. Good luck!
Joanne G  |  August 23, 2014
Comment on this post
By Randy
July 27, 2014
Randy wrote
Diabetic Symptoms with Zoloft
Been taking it since 2007. I have noticed symptoms similar to low sugar.
Sue  |  October 18, 2014
Comment on this post
By kellie
June 13, 2014
kellie wrote
self injury
1032views
Comment on this post
By Helen Melon
May 27, 2014
Helen Melon wrote
TRAZADONE STORY
2014views
I take this too. Doc put me on 100 mg. I'm 43 and weigh 200 lbs. I've never taken it on an empty stomach, but, the first time couple of times I took it, I actually got up in the middle of the night and did things while I was asleep! (sleep walking) as If I was awake. I'm just glad I didn't decide to go driving! So I cut my dose in half. I don't sleep walk anymore, but I do sleep on average 5-6 hours a night, straight. (Before taking it, I would wake up every 1-2 hours then spend 30 minu
Bryan  |  September 20, 2014
Absalootly
September 15, 2014
I've taken a lot of antidepressants and you should never start on a higher dose (I took a half pill my first night), they can really mess you up because the first few weeks you take them they can be stronger, and you are young. This is why you should never, never take a drug like this without a doctor overseeing you. You took too much, you should have tapered on and seen a doctor. Also, sleeping pills aren't meant for you to be able to walk around and do stuff after, but you're lucky somethi
notcool29  |  August 30, 2014
Hey, I take this medicine. Ive been on it for about a month now. When you take it you have to have food in your stomach, never take it on an empty one it will make you really sick. Also once it kicks in you HAVE to lay down and do not get up. Youll feel your limbs started to get heavy like its hard to even lift your own arm. You do get a very weird kind of heavy floaty feeling. If you stand you can faint, pass out, or black out. The room does spin. I know it can be kinda scary the first time bu
Kayley  |  July 28, 2014
Comment on this post
By user
April 8, 2014
user wrote
Zoloft
2379views
Comment on this post
By corrupted_jes
March 27, 2014
corrupted_jes wrote
Zoloft
1990views
Comment on this post
By SCREWEDFORLIFE
February 18, 2014
SCREWEDFORLIFE wrote
DO NOT TAKE TRAZADONE--MY HORROR STORY!!!
I checked in to see if there was any new info. I know many have taken this drug with NO reaction. Please realize bad reactions don't happen to everyone. But I want to warn of the POTENTIAL that this could happen. Wish somebody told me!!
SCREWEDFORLIFE  |  October 9, 2014
(god this editor is annoying! If I can't type that much, stop me! Don't let me type 500 characters then drop the last 200!) I stopped taking Ambien because the trazodone seemed to cover the sleeping problem. Now, clonazipam also helps you sleep, and is a longer lasting version of adivan, so I'm going to switch to that and see If I can drop down to just one pill :)
Bryan  |  September 20, 2014
Also, doc had me on Zoloft, Adderal, trazodone, ambien, and adivan, all drugs which, while they don't 'interact' they do entirely opposite things. Adderal 'perks' you up, while Zoloft calms you down. Adivan calms you down quickly, trazodone calms you down (and makes you sleep), ambien helps you fall asleep. So, why would I take Zoloft and adderal?! I stopped taking adderal because it caused me to need more adivan. I stopped taking zoloft cause it caused sexual side effects (being 'too calm
Bryan  |  September 20, 2014
SCREWEDFORLIFE.. You know it was Trazodone because your Urologist said so? You were also told it was a hernia, and cancer. You had 5 operations. Doesn't sound like anyone is really sure what's going on. Search all your drugs for their side effects.
Bryan  |  September 20, 2014
Thank you for sharing your horrible experiences. I will not use this drug
August 24, 2014
I have also been taking trazadone for years and have muscle pain cramps in that area sometimes after I urinate or at random times. I started eating healthier and taking supplements and it got better. I am very sorry for your injury my friend. Some where out there there is a doc that can fix you I hope. Keep looking don't give up !!
August 21, 2014
Patrick Do you work for the drug company ?
Class Action against Trazodone  |  May 31, 2014
I am a 16 year old female, I took Trazadone for the first time a few weeks ago, I wasn't prescribed but I'm diagnosed with insomnia so in desperate need I took 2 of my moms Trazadone pills, being stupid thinking that one wouldn't work but thinking that 2 would. That night I was already extremely stressed out from boy trouble and had very little if not any food in my stomach. About 15 minutes later I noticed the pills started to kick in and I felt like I had to throw up, from then I just decided
Helen Melon  |  May 27, 2014
LISA this is a dire t result of TRAZADONE. Reasearch the net and you will see MANY MANY men are impotent and cannot achieve a erection. When you view the litigation awards that total in millions to tens of millions depending on the case you can be DAM sure that those drug companies fought tooth and nail and LOST. If there was any chance this was just a coincidence you would not see men who have taken the same drug and have same side effect. And if read the warnings this directly states a side e
SCREWEDFORLIFE  |  May 22, 2014
I've been taking trazodone for sleeping. I've been on it for almost four years now. I've never had a bad experience or health issues. Are you sure it's the trazodone that is making you sick?
Lisa  |  May 22, 2014
I KNOW it was trazodone because my Urologist said so. If you take a look at TRAZODONE awards or lawsuits you will see awards for this same exact situation except not as many surgeries that settle in millions to tens of millions. I did my homework before I posted.
SCREWED FOR LIFE  |  May 21, 2014
Tried to say "not cheap" but ran out of space, I guess.
Kate  |  April 23, 2014
Trazodone does indeed cause priapism and this sounds like it could be related. Sadly, the doctor did not figure this out until the nerve damage had been done. For those with nerve pain, please google PEA Pure or Institute for Neuropathic Pain Netherlands. They have stuff in Europe for nerve pain and it can be imported now that the packaging has the proper English supplement facts on it. I have imported it and used it for nerve pain. It does help, but it takes awhile to kick in and it is not che
Kate  |  April 23, 2014
I'm sorry to hear that you have had such pain and that your lifestyle has significantly suffered; however, I do not believe that trazodone has caused any of your problems. They were probably pre-existing and you only noticed them at around the time you took trazodone. I am no expert but it sound like a normal human mistake associating oneproblem with a coincidental (false) "cause".
Patrick  |  March 25, 2014
Why is it that you think that Trazodone caused this? There is nothing in your story that gives a correlation between the two. What is causing your scrot pain?
Hizze  |  March 25, 2014
Comment on this post
By irishscottish
February 14, 2014
irishscottish wrote
celexa
1545views
Comment on this post
By Madison
January 8, 2014
Madison wrote
Zoloft Weightloss and Abilify
1967views
I started taking Zoloft about 3 weeks ago. I have been suffering with severe, medical depression, social anxiety and feelings of dread. I have good reasons to be depressed, as my Mom died of cancer 4 years ago, and I was diagnosed with Ovarian Cancer 2 years ago. Now I'm post menopausal at 39 and just can't cope. Immediately after taking Zoloft I began to feel good. Depression had become physically debilitating and I gained a lot I weight. I have also noticed a lack of desire for food, and have
Beana  |  July 4, 2014
I also have to take Diflucan/flucanozole occaisionally while taking Zoloft...never any problems.
debra  |  March 31, 2014
Zoloft saved my life. Outside of my wonderful husband it is the thing in life I am most grateful for. Much better than Prozac where I always felt medicated.It is not for everyone but if doc recommends it, I would try it. Just pay attention and give it some time and if you have any side effects do not wait to address them...do it immediately.
debra  |  March 31, 2014
Comment on this post
By Kay terfinko
December 20, 2013
Kay terfinko wrote
Zoloft and gallbladder
1040views
Comment on this post
By Willie DeJarnette
December 3, 2013
Willie DeJarnette wrote
Zoloft Weight Loss
3344views
Comment on this post
By agnes
November 30, 2013
agnes wrote
heart pounding
1202views
OMG you have just helped me - I get the racing heart, and now that I think about it, its after a couple of glasses of coke zero
Amy  |  August 20, 2014
I find I get way more severe reaction to caffeine when I am on Zoloft. Have to drink caffeine free coke!
Otherwise I get a racing heart, exactly like a panic attack. Took me ages to figure out, I thought they were panic attacks!
Frankie  |  June 10, 2014
Its suppose to slow your heart down...
April 28, 2014
Comment on this post
By Girl555
November 26, 2013
Girl555 wrote
does anyone know if it's a smooth transition from Cymbalta (Duloxetine) to Trazodone?
Cymbalta is now out as a generic form and should be more affordable if you want to stick to what is working for you.
JustFYI  |  October 29, 2014
You will need to taper off Cymbalta regardless of what drug you switch to. However, you could start Trazodone right away, I'm on both with no problems. But start taking less of Cymbalta over 2-3 weeks or you will have nauseau, headaches, etc. They call it 'discontinuation syndrome' - you're not addicted but your your brain has trouble adapting to going off it so quickly. I usuually start taking longer and longer time between doses. You can also open the capsules and pour a little bit out e
Vessel323  |  August 30, 2014
Try getting another drug... We are after the FDA to have this drug removed
Class Action against Trazodone  |  May 31, 2014
I have the same swallowing problem with Trazadone but not a breathing problem. I don't eat after taking it and drinking water or milk isn't a problem. Might want to check the dose
Jarbwa23  |  February 7, 2014
Comment on this post
By PG
November 10, 2013
PG wrote
Positive experience
1640views
trazodone works for my chronic insomnia but with lots of side effects ,eg muscle pain mood swing and nightmares
kerry  |  September 3, 2014
it increase your body mass but its good for sleeping
kerry  |  September 3, 2014
Comment on this post
By LisaB
October 27, 2013
LisaB wrote
Zoloft and neck stiffness
1029views

I take 150mg Zoloft and have the sore nipples and the sore stiff neck which is horrible but this really does work on your neck it has 2 sticky pads connected to this portable device just stick them where the pain is on your neck for the night and you'll feel wonderful in the morning ??
BarbaraMay  |  October 27, 2014
I put mine neck ache down to stress, but if it is a common side affect of Zoloft maybe I'm not super stressed
August 20, 2014
i am taking Mirtazapine and sometimes Lorazepam and sometimes xanax and I too get these stiff necks and just does not subside - i have had them for the last 2 months now - any advice?
rr98  |  July 14, 2014
Same thing with me I have horrible neck pain
And stiffness and a headache and I also take zoloft
Megan  |  June 27, 2014
I take Zoloft and had horrible neck pain from out of no where.. Wonder if it's from that my dr prescribed my flexerol for it.
May 28, 2014
Same thing, neck pain for months now. Diagnosed for RA now, and prescribed Methortexrate.
mike  |  May 6, 2014
Yes, I also take Zoloft and have bad neck and back stiffness. It does seem to subside after awhile. Try heat and stretches...good luck.
Cheryl  |  February 18, 2014
Comment on this post
By Caroline
September 16, 2013
Caroline wrote
trazadone and swallowing problem
1092views
This is normal the first week or so. Just make sure you have plenty of water beside your bed.
craig  |  September 22, 2014
I had trouble swallowing as well, and when you take Trazadone with Caffiene, you could end up in ER with crazy high blood pressure. Ugh
TC  |  August 12, 2014
Comment on this post
By Nia
September 8, 2013
Nia wrote
Suicidal
Comment on this post
By kwissy
September 6, 2013
kwissy wrote
shaky hands
Hi, I have a 12 yr old son...just hope you get better and that u have some people in your life who love u as much as I love my son. If u don't, keep looking, you will find people who care. Good luck, and if the Zoloft feels bad for you, tell your dr. I'll be hoping you are ok. ;-))
Jaipria  |  June 22, 2014
Im glad Zoloft has helped with your depression however it didnt help with mine. I would talk with your doctor about the shaky hands. I stopped taking Zoloft awhile ago and I still have shaky hands from it.
jp  |  June 8, 2014
Comment on this post
By When1Was
August 25, 2013
When1Was wrote
Great for gaining weight, bad for sleeping!
2159views
Comment on this post
By Maegan
August 1, 2013
Maegan wrote
trazadone & nausea
Comment on this post

What patients are saying about Trazodone vs. Zoloft

3,619 patient discussions from healthcare websites and blogs
my doctor prescribed me both zoloft (which is also an SSRI)...
my doctor prescribed me both zoloft (which is also an ...trazadone would make the zoloft work better... this was almsot 3 ...any bad reactions. the trazadone hardly worked for my insomni...
trazadone and neither of those worked for me. I still...
I tried zoloft, trazadone and neither of those worked for me. I still feel this deep depression, anxiety, irritable, etc. How fast does it usually...
trazadone and neither of those worked for me. I still...
I tried zoloft, trazadone and neither of those worked for me. I still feel this deep depression, anxiety, irritable, etc. How fast does it usually work??? Added 23 Apr...
100mg. (niether work for sleep or depression) Plavix...
Yes, no problem. Right now I'm on Zoloft 200mg. Trazadone 100mg. (niether work for sleep or depression) Plavix for thining my blood due to a stroke in 1994. Vytoron for stroke prevention. Nexium for...
night the same time I take the trazadone. It works for...
...and Trazadone. I am on 150 mg of Zoloft and 100 mg ...use to take the Zoloft in the a.m. (that was for about 10 years with no side effects), but after a stomach ...I take the trazadone. ...
Zoloft and Trazodone and still having major sleep problems...
...diagnosed with fibromyalgia 10 years ...tried Cymbalta and Trazodone, but I could not stomache the Cymbalta. I am now on Zoloft and Trazodone and still having major sleep problems. During the...
and trazodone doesn't really help me sleep, sometimes it...
...trazodone and addreall, zoloft. The medicament are not working like before. Just ...I am taking trazodone and addreall rx ...weeks ago, and trazodone doesn't really help me sleep, sometimes i...
added. I had a bad reaction to Trazadone prior to the...
...'98. My doctor then put me on Zoloft because of irregular, ...from insomnia. My Zoloft has been cut in half and Serazone added. I had a bad reaction to Trazadone prior to the Zoloft. Also prescr...
felt like i could think critically and was doing really well...
...of zoloft made me jittery while the 50 made me sleepy and a zombie. After 2 weeks on the zoloft I felt like i could think critically and was doing really well, and ...started taking the trazodo...
and have been on it for 15 years with no side effects...
...wakeup feeling groggy. But the medicine makes me really constipated! I have been taking stool softeners at night but no help. I know its kind of weird to bring this up but if anyone has suggestions...
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