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Tizanidine vs. Trazodone for Fibromyalgia

Tizanidine

Rx
/ 3,529 posts
Other Names: Zanaflex

Trazodone

Rx
/ 69,871 posts
Other Names: Desyrel   Molipaxin   Oleptro
Rating: 2.5 out of 5
Based on 3,529 patient discussions on healthcare websites and blogs
Learn more
Rating: 3.5 out of 5
Based on 69,871 patient discussions on healthcare websites and blogs
Learn more
Tizanidine (trade names Zanaflex, Sirdalud) is a drug that is used as a muscle relaxant. It is a centrally acting 2 adrenergic agonist. It is used to treat the spasms, cramping, and tightness of muscles caused by medical problems such as mul... Read more on Wikipedia
Trazodone (also sold under the brand names Desyrel, Oleptro, Beneficat, Deprax, Desirel, Molipaxin, Thombran, Trazorel, Trialodine, Trittico, and Mesyrel) is an antidepressant of the serot... Read more on Wikipedia
Concern level
Top 3 Concerns
Drowsy
Did you have
this too?
Insomnia
Withdrawal
Concern level
Top 3 Concerns
Sedation
Did you have
this too?
Sleepy
Groggy
See all concerns, alternative treatments and more
See all concerns, alternative treatments and more
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Help people by sharing experiences you've had with Tizanidine or Trazodone - your story could impact others.
Treato My Voice
By Helen Melon
May 27, 2014
Helen Melon wrote
TRAZADONE STORY
Comment on this post
By sami
March 1, 2014
sami wrote
tizanidine with worse depresion, stomach problems and NO sleepiness!
Comment on this post
By SCREWEDFORLIFE
February 18, 2014
SCREWEDFORLIFE wrote
DO NOT TAKE TRAZADONE--MY HORROR STORY!!!
4386views
Patrick Do you work for the drug company ?
Class Action against Trazodone  |  May 31, 2014
I am a 16 year old female, I took Trazadone for the first time a few weeks ago, I wasn't prescribed but I'm diagnosed with insomnia so in desperate need I took 2 of my moms Trazadone pills, being stupid thinking that one wouldn't work but thinking that 2 would. That night I was already extremely stressed out from boy trouble and had very little if not any food in my stomach. About 15 minutes later I noticed the pills started to kick in and I felt like I had to throw up, from then I just decided
Helen Melon  |  May 27, 2014
LISA this is a dire t result of TRAZADONE. Reasearch the net and you will see MANY MANY men are impotent and cannot achieve a erection. When you view the litigation awards that total in millions to tens of millions depending on the case you can be DAM sure that those drug companies fought tooth and nail and LOST. If there was any chance this was just a coincidence you would not see men who have taken the same drug and have same side effect. And if read the warnings this directly states a side e
SCREWEDFORLIFE  |  May 22, 2014
I've been taking trazodone for sleeping. I've been on it for almost four years now. I've never had a bad experience or health issues. Are you sure it's the trazodone that is making you sick?
Lisa  |  May 22, 2014
I KNOW it was trazodone because my Urologist said so. If you take a look at TRAZODONE awards or lawsuits you will see awards for this same exact situation except not as many surgeries that settle in millions to tens of millions. I did my homework before I posted.
SCREWED FOR LIFE  |  May 21, 2014
Tried to say "not cheap" but ran out of space, I guess.
Kate  |  April 23, 2014
Trazodone does indeed cause priapism and this sounds like it could be related. Sadly, the doctor did not figure this out until the nerve damage had been done. For those with nerve pain, please google PEA Pure or Institute for Neuropathic Pain Netherlands. They have stuff in Europe for nerve pain and it can be imported now that the packaging has the proper English supplement facts on it. I have imported it and used it for nerve pain. It does help, but it takes awhile to kick in and it is not che
Kate  |  April 23, 2014
I'm sorry to hear that you have had such pain and that your lifestyle has significantly suffered; however, I do not believe that trazodone has caused any of your problems. They were probably pre-existing and you only noticed them at around the time you took trazodone. I am no expert but it sound like a normal human mistake associating oneproblem with a coincidental (false) "cause".
Patrick  |  March 25, 2014
Why is it that you think that Trazodone caused this? There is nothing in your story that gives a correlation between the two. What is causing your scrot pain?
Hizze  |  March 25, 2014
Comment on this post
By Girl555
November 26, 2013
Girl555 wrote
does anyone know if it's a smooth transition from Cymbalta (Duloxetine) to Trazodone?
Try getting another drug... We are after the FDA to have this drug removed
Class Action against Trazodone  |  May 31, 2014
I have the same swallowing problem with Trazadone but not a breathing problem. I don't eat after taking it and drinking water or milk isn't a problem. Might want to check the dose
Jarbwa23  |  February 7, 2014
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By PG
November 10, 2013
PG wrote
Positive experience
1020views
Comment on this post
By Caroline
September 16, 2013
Caroline wrote
trazadone and swallowing problem
Comment on this post
By When1Was
August 25, 2013
When1Was wrote
Great for gaining weight, bad for sleeping!
1411views
Comment on this post
By Maegan
August 1, 2013
Maegan wrote
trazadone & nausea
Comment on this post

What patients are saying about Tizanidine vs. Trazodone

54 patient discussions from healthcare websites and blogs
recently went off Tizanidine and started taking Trazodone....
...just recently went off Tizanidine and started taking Trazodone. Didn't realize there was ...Tramadol. I was taking Tramadol, but d...
Sometimes I take Tizanidine which mostly just...
...strongest drug that I use is Gabapentin...I also take Trazodone at bedtime and amitriptylline. Sometimes I take Tizanidine which mostly just puts me...
Now I take tizanidine (another muscle relaxant.) Benadryl...
...Flexeril for years. A few months ago, my insurance stopped paying for it. Now I take tizanidine (another muscle relaxant.) Benadryl does nothing ...them. I take Trazodone at bed...
also, but could not tolerate the side effects. I've...
I have tried Trazadone, also, but could not tolerate the side effects. I've tried lots of drugs for sleep, but ...for a while - is Zanaflex (Tizanidine 4mg)(muscle relaxer). I take 1/2...
If it's my trazodone I'm screwed. Besides how much it...
...every night. If it's my trazodone I'm screwed. Besides how much it helps me I have to withdraw from it. The last time this happened it was tizanidine. Glad you figured yours out...
up? I was great with Trazodone and suntheanine. I'll...
...Odd about the tizanidine. I'm ok for ...my brain up? I was great with Trazodone and suntheanine. I'll blame Valtrex. Evil stuff. I ...kid that I had problems sleeping. The slightest n...
for headaches. I also take Tizanidine. I use a pain roll...
...at bedtime which is a pain pill. I take Excedrin migraine for headaches. I also take Tizanidine. I use ...strength Advil. I know you want to enjoy your little sweetie. I have two amazing grandda...
take Tizanidine(Zanaflex) and Trazadone(you may not be able...
I take Tizanidine(Zanaflex) and Trazadone(you may not be able to take this in addition...
I found Trazadone great for sleep, I can't take it because...
I'll have to look up Tizanidine, I've never heard of it! I found Trazadone great for sleep, I can't take it because ...you! Upping the Gabapentin has made a HUGE difference for me. I wish the...
I'm going off the Tizanidine (muscle relaxer) and adding...
...extremely concerned about becoming addicted to Hydrocodone/Vicodin. He probably explained to ...Anyway, I guess I'm going off the Tizanidine (muscle relaxer) and adding Trazadone. Giving it a co...
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