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Predicting the success of Tecfidera

Tecfidera (BG-12)

/ 5,594 posts

Positive Experiences with MS Medications Change usage

Based on 5,594 patient discussions on healthcare websites and blogs. Learn more
Get more info! Tecfidera (BG-12)5,594 posts
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Tecfidera (BG-12) Top Concerns

Based on 5,594 patient discussions on healthcare websites and blogs
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By Ratsy70
August 9, 2014
Ratsy70 wrote
Just started Techfidera
Started Techfidera August 5, 2014

Aug 5- Had no side effects.
Aug 6- Mild Headache but went away
Aug 7- Had some body aches later in day
Aug 8- Woke up with body aches that hurt throughout the day.
Aug 9- Woke up with no side effects :D :D :D

Overall I'm having a great experience on Techfidera. I never had the lobster red flushing or rashes. I'm very excited to have switched to Techfidera from Copaxone.
Comment on this post
By Nata
August 2, 2014
Nata wrote
1st day on Tecfidera
Took my first dose@9 a.m & turned beat red, flushing & itching for almost 2 hours. Not terrible but am really sleepy very concerned w/that symptom. Anyone else sleepy?
I started taking it in May of '14 & no rash or stomach pain. I am sleepy all the time. I could fall asleep tight now. Not sure it's a side effect but was not like this a year ago. Best of luck! I'm here for you XXXX@aol.XXXcom Richie
Richie  |  August 24, 2014
Hang in there...it gets better...
August 20, 2014
Took 2nd dose tonight - Yes, I feel sleepy too. With my first dose this morning - I also turned beet red all over (rash), had some flushing and mild itch. With 2nd dose - My throat feels weird but no flushing and I don't have the rash.
Crystal  |  August 10, 2014
Comment on this post
By Leslie
July 24, 2014
Leslie wrote
Allergic reaction to Tecfidera
I have been on Tecfidera for 7 months for MS. I was so happy not to be doing the injections. I had the flushing and was not having any problems and all of a sudden had a terrible rash over my whole body. I went to the dermatologist put me on steroids and did a skin test. She thought it was an allergic reaction to my medicine. Called neuro and nurse said to go off for a week. My rash just started to go away. Started bac on this morning, within 2 hours was covered in a bright red color, started to itch and was so hot to the touch. I am afraid to stay on it. I called the drug company and they said they never had anyone with a bad rash. I find it hard to believe no one else has reported this. Did anyone else have this happen? This is much more than flushing. Is there any other med for MS that is in pill form? I was hoping this wasn't the Tecfidera, I thought after 6 months of being on it, I was home free.
I have started getting daily allergic reaction type rashes. Don't seem to get them (at least not as bad) if I take allergy medicine too. Mine tend to last about an hour & then go away. but it is hot, red, itchy...awful when it happens.
November 12, 2014
restarted Tecfidera after a week since my last dose. A few hours after taking first dose, I was completely red all over. Changed clothes into something more loose and sat under a fan. My second dose, a few hours later, I could feel it again and started watching myself turn red again. Drank ice water, and used moist towel to cool my skin. Redness reduced within an hour. Never had it happen when I started it, but maybe being off for a week and then restarting at the full dose was too much
msfireant  |  October 25, 2014
Try taking a low dose aspirin a half hour before each dose, and take it on a full stomach, with peanut butter, or some other healthy fat. It helps with absorption, and prevents flushing. If it continues, try taking Zyrtec once a day. It may just be that Tec isn't for you, in which case, there are other pills, such as Gilenya and Aubagio. But, Tec has less side effects, so I would try to see if the rash will go away, first.
August 17, 2014
I had a rash with red spots on my right leg. I was taking Tecfidera and amoxicllin. My doctor thinks its impetigo, but there is no discharge. I remember I was on medication once and had the same kind of reaction. Not sure if this helps, but thought I would mention it anyway. No flushing but rash on one leg with mild itching. Was told if its get worse to go to dermatology. I have finished the amoxicillin and rash is disappearing.
Unsure  |  August 11, 2014
Comment on this post
By 2
June 11, 2014
2 wrote
My first week
I was diagnosed with MS last month and I just began Tecfidera this week. The first pill I took resulted in an hour long episode of facial flushing and nausea. After one hour, that subsided. Every pill after that resulted in no symptoms.

I am so happy that I'm not experiencing any acne or hair loss--those were my major concerns. I will update again after starting my stronger dose in a few days.

Yikes! Hair loss?!
Nata  |  August 2, 2014
One of the things that can be problematic is taking the Tecfidera while on an antibiotic. Tecfidera is an Immune suppressant So the antibiotics and and Tecfidera don't work together. Tecfidera slows down the immune system and antibiotics speed it up.
Ginger  |  July 18, 2014
Comment on this post
By Verna
May 3, 2014
Verna wrote
Tecfidera and weight loss
Hi, I have been on the Tecfidera for two months, I have lost 10lbs in that time. All my Docs have been informed and say if I hit 15, I need to contact them again. Actually I like the weight loss as I can afford to lose some. Not much more however. The Tecfidera has been awesome, no other issues with this medication, love it, so far...
Nice, are now welcoming the comments about its initial decision of the groups of patients, health professionals and others. I suggest you to join that discussion about Tecfidera healthauthoreviews.com
elizaissac  |  September 22, 2014
Comment on this post
By Myachinghead
January 16, 2014
Myachinghead wrote
I have a history od severe migraines (not uncommon in individuals wiyh brain lesions) and needed to discontinue Avonex (after 7 good years) due to recalcitrant migraines. I started Techfidera 3 weeks ago and have had a migraine every day for the past 8 days. The headaches respond to my rescue medicines, but nothing prevents them or relieves them other than the rescue meds.
Comment on this post
By Martha Jones
December 30, 2013
Martha Jones wrote
lst day of 120 mg of Tecfidera. Itching and seems like fire inside my body. Took one benadryl after taking the second pill and it seems to be helping.
Comment on this post
By Vanessa
December 17, 2013
Vanessa wrote
Weight Loss
I started taking Tecfidera in July. In the beginning I experienced the flushing and some constipation. Overall I have done really well on the drug. I wanted to know has anyone else expereinced weight loss on Tecfidera. I thought I was under stress, but this morning when I tried on some pants I realized it had to be something else. Finally, I decided to check the website. I'm 5'4 and I really can't afford to loose weight. Does anyone have any suggestions?
Loss of appetie almost immeadiatly. After 2.5 weeks, I need to set a timer to remember to eat.
JHS  |  June 25, 2014
I have been on Tec 2 weeks and am experimenting weight gain w/ hunger.
Lilly  |  April 4, 2014
I started on the tec November 2013, and started dropping a little weight consistently until I stopped it just 2 weeks ago. I would have stayed on it but for the other side effects- debilitating nausea, headaches, tooth and gum lesions and pain and hair loss. When I was asked by someone if I had cancer (because of the weight loss) that was enough for me. I should have known better than to consume cleaning products even if they have "reformulated" it and put it in a capsule. I'm getting tir
Cyndie  |  March 29, 2014
Why Tec? I see no weightloss info on it...
Ramprat  |  February 26, 2014
I've been on Tecfidera about four months now and have lost 20 pounds. While I walk miles and miles every day and eat really well, I haven't really changed diet or exercise.
Kristin  |  January 28, 2014
I've been on Tec for over 3 months now. I've lost about 15lbs w/o dieting or much exercise. Going to see the dr soon
SoccerDad  |  January 26, 2014
Comment on this post
By Linda
December 12, 2013
Linda wrote
Debating with Dr whether or not to start the drug. Have been on all of them over the past 10 years and just can't do the injections any longer. So tired of all the side effects and the trouble of doing them. Dr told me to research this one and see what I think. I have read everything I can find on it now I want to know what the people that are actually taking it really think. Just wondered if people are staying with it when they start and how it is going for them?
Feeling the same regarding MS meds. I've been off of Copaxone (injections) for almost 8 years. We just had 2 car accidents and I'm so fearful of more flareups so I began Tecfidera the other day. Yes, the flushing, itchy deal is a nuisance but it's the effect of being tired that I'm having a hard time with. Not at all happy about that! It's bad enough when MS symptoms create a sluggish feeling, now that coupled with this med, stinks.
Nata  |  August 2, 2014
One of the things that can be problematic is taking the Tecfidera while on an antibiotic. Tecfidera is an Immune suppressant So the antibiotics and and Tecfidera don't work together. Tecfidera weakens the immune system and antibiotics strengthen the immune system.

I would highly advise that if you have any kind of infection and are about to start a regime of Tecfidera consult your doctor and do not start until you are infection free.
Ginger  |  July 18, 2014
I have been on Tecifedera for 8 months now and it has been a blessing. I have not had a flareup since on it whereas before it was everyother month. The flushing can be avoided by taking an aspirin with it...it really is a great medication! I recomend switching to it.
Megan  |  May 31, 2014
Comment on this post
By Marcia
September 5, 2013
Marcia wrote
Day 8 terrified still of side effects but ALL minor to date! Feeling upbeat at times then exhausted at others. Moving around more, smaller appetite, some warmth feelings and chills but as mentioned minor. Take with food and water, I take a probiotic and other supplements, stationary bike 1 - 2 mile 4xweek. Homeschool autistic son, great for my mind. Mobility went way down this past year(walker/wheel chair) and time for treatment.
I had been on Rebif 7 years but could not tolerate it any more. That was 3 years ago. Start date date of tecfidera August 29, 2013. Full speed ahead with this med. Well wishes to you all.
Pam I also am experiencing extreme fatigue. I am not sure if it's just my MS or if the drug is making it worse. I feel like my arms and legs have weights attached to them.
Ann  |  March 11, 2014
I recently switched from Copaxone, after 10 years. I had no injection sites left. I have been on Tecfidera about 7 months. My recent MRI scans is stable. I still flush, intermittently, several hours after meals. Benadryl handles it well. The major side effect that I have is extreme fatigue. This is different than my normal MS fatigue. I am trying to stick with it to see if after time, it subsides. Hope this helps!
Pam  |  January 6, 2014
Hi Marcia, I do not take Tecfidera but am considering it. I have taken copaxone for over ten yrs. now and have had some flares with optic neuritis, heavy legs with difficulty walking and some fat destruction in my legs where shots are done but Copaxone seems to be working and I feel very stable. I do try to stay out of the sun and to keep my stress as low as possible (read Bible for this every p.m.). I am looking into Tecfidera as I would like to stop taking shots daily. jane
jane  |  September 16, 2013
Comment on this post
By Cheryl Baker
August 22, 2013
Cheryl Baker wrote
I've been on Tecfidera for about 3 months...
I never had any flushing while on the starter kit (low dose). As soon as I went to the higher dose, I had a lot of flushing and itching. Every once in a while this still happens but Benadryl clears it right up. Also, with the higher dose, I have begun spotting and/or lightly cramping. Has anyone else had a similar experience?
I've been on Tecfidera for about a year and after an 8 year remission stretch of Crohn's or Colitus (they couldn't concretely say which one I have) it's BACK!!! Asacol, a treatment for Crohn's, isn't working so now I have ot get off of Tecfidera and will likely go on Azathioprine to get Crohn's under control. This is bad, really bad folks. Azathioprine is very dangerous and it may not help my MS, but the Crohn's is getting so bad I have to let it take precidence over MS. I see online that Tecfi
Tecifidera and Crohn's?  |  September 8, 2014
Trisha, I hope you are still hanging in there. The simplest thing for me made all the difference in the "furnace effect". I read somewhere else that several people took aspirin an hour before Tecfedra. The flushing and heat is so minor now that I do that. I have a lot of hope hanging on this medicine as well. Let's hang on together!
Anne Marie  |  August 25, 2014
It does get better, Trisha. For me it is an every once-in-a-while side effect. It only happens maybe once every 2-3 months.
Cheryl Baker  |  June 10, 2014
I just started low dose 120 mg Tecfedra. I'm just now 3d week getting the sweats.
I'm getting real horrible sweats ( flushing ). I haven't even begun the 240 mg dose &
I'm bout ready to throw in the towel. I'm so misrable. I haven't been able to stay on
anything, this was my really big hope! Does this constant heat go away? Feels like Im
A furnace on the inside. I get dripping wet. Just begun on third week too. I thought this time
I'd make it. Anyone else have this problem ?
Trisha  |  June 10, 2014
I've been on the Tecfidera for a month and now am having unusually heavy cycle that came 2weeks early.
Michelle  |  May 16, 2014
I have been on it for 6 months and have not had those issues.
Pam  |  January 6, 2014
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What patients are saying about Tecfidera (BG-12)

5,594 patient discussions from healthcare websites and blogs
and I am currently on Tecfidera. I'm not sure how, but...
...with CIS, not MS (yet) and I am currently on Tecfidera. I'm not sure how, but insurance accepted it and I've been on it since August. It's...
So am I and Im on Tecfidera pills they work for me and only...
...You said you are RRMS. So am I and Im on Tecfidera pills they work for me and only have the flushing issue. you might ask if it could work for you. My MS has been...
How have you been while on Tecfidera?any new side affects ,...
...recently diagnosed this past July, RRMS. I am doing my research on treatment along with assistance from my Doctor. How have you been while on Tecfidera?any new...
this year. I have been on Tecfidera for 9 months as of...
I have RRMS and have had it for 10 years this year. I have been on Tecfidera for 9 months as of July 10th of this year. I just noticed ...It is only located in the center and I have no pain anywher...
April 2014 and have been on Tecfidera for a little over 2...
I am newly diagnosed with MS in April 2014 and have been on Tecfidera for a little over 2 ...and a CT scan. I am on birth control pills and usually have just a ligth 3-4 day period, but I have had...
Fumaric acid from which BG-12 is derived is documented to wo...
...stems from my treatment path of fumaric acid. Fumaric acid from which BG-12 is derived is documented to work by enhancing TH2 response. But what I can't resolve in my head is --I have PPMS, which...
effects Hi all! Started Tecfidera about 10 days ago and...
Side effects Hi all! Started Tecfidera about 10 days ago and ...nausea and stomach pain. My MS dr actually had me ...of this. Anyone else experience nausea/stomach pain? So hard not...
was really hoping tecfidera would cure mine, but so far, no...
That does sound strange. I have psoriasis - have had it for 3 or 4 years now. I was really hoping tecfidera would cure mine, but so far, no luck. I'm on a slow titration. 1 120 mg for 28 days,...
on tec for 6mos. I had mild stomach ache and some bloating...
...on Tecfidera I have been on tec for 6mos. I had mild stomach ache and some bloating at...
Tecfidera for two full weeks. I experience flushing, itching...
I have only been on Tecfidera for two full weeks. I experience flushing, itching without a rash, and...