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Seroquel

Rx
/ 153,482 posts
Other Names: Quetiapine   Seroquel XR

Zyprexa

Rx
/ 61,702 posts
Other Names: Olanzapine
Rating: 3.5 out of 5
Based on 153,482 patient discussions on healthcare websites and blogs
Learn more
Rating: 3.5 out of 5
Based on 61,702 patient discussions on healthcare websites and blogs
Learn more
Quetiapine (branded as Seroquel, Ketipinor), is an atypical antipsychotic approved for the treatment of schizophrenia, and bipolar disorder.Annual sales are approximately $5.7 billion worldwide, and $2.9 billion in the United States. The U.S... Read more on Wikipedia
Olanzapine (trade names Zyprexa, Zalasta, Zolafren, Olzapin, Oferta, Zypadhera or in combination with fluoxetine Symbyax) is an atypical antipsychotic, approved by the Food and Drug Administration for the treatme... Read more on Wikipedia
Concern level
Top 3 Concerns
Weight Gain
Did you have
this too?
Tiredness
Addiction
Concern level
Top 3 Concerns
Weight Gain
Did you have
this too?
Diabetes
Tiredness
See all concerns, alternative treatments and more
See all concerns, alternative treatments and more
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Help people by sharing experiences you've had with Seroquel or Zyprexa - your story could impact others.
Treato My Voice
By kelly
August 26, 2014
kelly wrote
seroquil
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By lablanche
August 1, 2014
lablanche wrote
haldol vs seroquel
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By Healthy Jack
July 30, 2014
Healthy Jack wrote
acupuncture and back pain
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By Mesbahi Dr Roy's patient
May 22, 2014
Mesbahi Dr Roy's patient wrote
Zyprexa and stretch marks
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By Thomas
April 6, 2014
Thomas wrote
Extreme Energy
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By Dave
February 8, 2014
Dave wrote
Olanzapine and diabetes
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By angelajhn
December 17, 2013
angelajhn wrote
depression
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By littlemissupanddown
November 27, 2013
littlemissupanddown wrote
olanzapine and carpal tunnel
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By alan
November 9, 2013
alan wrote
Quetiapine , and cognitive Impairment
Everyone has different reasons for insomnia and everyone's body reacts differently to meds. Its good to share experiences, but you have to learn for yourself what works best. Sometimes doctors are no help, other than providing access. I hadn't fallen asleep without meds for 15 years and tried most meds mentioned, along with every herb, otc, nonlegal alternatives. I can finally now fall asleep most nights on my own, but wake up in 3-4 hours. But that's progress. Good luck to you all.
Ron  |  August 28, 2014
I have been dealing with MDD and I started taking Seroquel a few weeks ago, 100 mg at bedtime. In addition, I have started taking Effexor; initially 37.5 mg twice a day, just switched to 50mg twice a day.
I feel as though I am just coming out of anesthesia, pretty much the entire day. I can't function normally. My head is in a fog and I don't feel safe driving. This is nuts. How am I supposed to hold down a job?
I am hoping hoping HOPING my body adjusts to these 2 meds, otherwise, I am asking
woolf  |  August 8, 2014
"It really doesn't make sense to me how drugs such as Quetiapine achieve their supposed "anti-psychotic" effects.

My first impression would be that antagonism of 5-HT2a receptors would worsen the negative symptoms of a psychosis by causing confusion and cognitive dissonance.

Also, wouldn't the anticholinergic effects of such drugs contribute to psychosis? Short-term memory impairment is perhaps the main underlying attribute of a psychosis -- wouldn't anticholinergic activity worsen problems
Of course it causes cognitive problems  |  August 3, 2014
There are multiple anti-depressant medications. Consult your prescribing physician on your reactions to your medication. Keeping a journal helps, & will aide in getting you on the right dose or prescription.
June 26, 2014
I've been taking 400-450 mg of Seroquel for over 10 years. I was for
tunate to be treated by a very good Neuro Psychiatrist who has now retired. While taking more than 400mg can cause insomnia. Lower doses of 50-100mg can act as a sleep aid. I function best by taking it all at bedtime along with a sleep aid. When I had to find a new doctor, the first thing he did was screw with my Meds. I should have listened to my instincts, and changed only one med at a time. He changed me too 400mg at nigh
Mer  |  June 8, 2014
I have been on Quetiapine for about 10 years now, it does take a long time to get used to the effects of this drug both good and bad. One thing to remember is, you are used to the way your mind worked before taking the drug, and have to learn how your mind works after taking it. Yes after taking it you will become impaired, it is a very strong tranquilizer. I started on 200ml per day, 25 ml 4 times a day, 100ml at bedtime it took about a year or even 2 before I learned to function while on this
Kellin  |  June 1, 2014
I am feeling the same way, I have been taking 50mg for two weeks a the doctor raised me to 50 mg at bed and 25 mg in the morning. I am fatigued, down, not able to think clearly. This is crazy, I feel that I'm go into depression because of my symptoms.
Rusty  |  March 17, 2014
antipsychotic meds are too much risk to be used off-label
i'm not a comedian  |  January 13, 2014
Its not a sleep aid , you should try something approved for sleep , its a anti psychotic , if your not psychotic don't take it ,
adam  |  January 3, 2014
Comment on this post
By LiveWithPTSD
August 30, 2013
LiveWithPTSD wrote
The light switch
Thanks for the thoughtful post. I was also an eldest. Given my emotional makeup, being very responsible, always the good girl the responsibility of caring for siblings, carrying out chores, attempting to keep peace & unsuccessfully lead my charges to pull their share of the work at a young age took a toll on me too.
I was shy at school & moved every other year. I found relief in theater arts playing characters not me. Later I was discouraged from pursuing theater as a career. Music & books f
mustfindbetterway  |  January 23, 2014
Comment on this post

What patients are saying about Seroquel vs. Zyprexa

9,521 patient discussions from healthcare websites and blogs
lbs I had gained on Zyprexa because my appetite decreased....
...I was first diagnosed as major depressive with psychotic features. The Seroquel helped me lose 50 lbs I had gained on Zyprexa because my appetite decreased. But after taking the Seroquel...
which does work for me but has also made me gain weight...
...didn't do anything for me except make me gain weight. i was then switched to zyprexa which does work for me but has also made...
difference...I feel so much better on Zyprexa!!! The Zydis...
...on Seroquel. I only gained weight on Seroquel if I ...exercising. I believe weight gain with Zyprexa will be similar to Seroquel with one difference...I feel so much better on Zyprexa!!! The Zy...
lost all the weight I gained on zyprexa when I switched to...
...yrs after I took zyprexa. I lost all the weight I gained on zyprexa when I switched to Seroquel. it was a...
after zyprexa made me gain a lot of weight. it sadly...
...took seroquel after zyprexa made me gain a lot of weight. it sadly didnt help sleep and didnt ...all. now im on risperdal, hope...
so YMMV! I gained weight on both Zyprexa and Seroquel but...
Yep, that's why meds are so YMMV! I gained weight on both Zyprexa and Seroquel but have lost all that I gained while taking Wellbutrin. I think I've heard of maybe two or...
same reaction to seroquel. My doc switched me to zyprexa,...
...reaction to seroquel. My doc switched me to zyprexa, and am doing much better...
needed a lower dose , comparing to zyprexa , to feel well ....
...from Zyprexa 10mg , to Seroquel 100mg for me It was a very good change , no weight gain , improvement in my anxiety , and I needed a lower dose , comparing to zyprexa , to feel well . I...
difference...I feel so much better on Zyprexa!!! The Zydis...
...than on Seroquel. I only gained weight on Seroquel if I ...exercising. I believe weight gain with Zyprexa will be similar to Seroquel with one difference...I feel so much better on Zyprexa!!! T...
didnt cause me any weigth gain and Zyprexa made me a...
...hello seroquel mostly works for my depression and anxiety, ... I tooke Zyprexa first on my life and then I changed to Seroquel . They worked ...didnt cause me any weigth gain and Zyprexa ...
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