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/ 38,878 posts
Other Names: Aleve   Naprosyn   Naproxen Sodium   Anaprox   Midol


/ 406,231 posts
Rating: 3 out of 5
Based on 38,878 patient discussions on healthcare websites and blogs
Learn more
Rating: 3 out of 5
Based on 406,231 patient discussions on healthcare websites and blogs
Learn more
Naproxen sodium (International Nonproprietary Name) is a nonsteroidal anti-inflammatory drug (NSAID) commonly used for the reduction of pain, fever, inflammation and stiffness caused by conditions such as:* osteoarthritis* kidney stones* rheumatoid arth... Read more on Wikipedia
Prednisone is a synthetic corticosteroid drug that is particularly effective as an immunosuppressive drug drug. It is used to treat certain inflammatory diseases and (at higher doses) some types of cancer, but has significant adverse effects. Because it ... Read more on Wikipedia
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Treato My Voice
By gardenerbychoice
March 30, 2014
gardenerbychoice wrote
Meloxicam helps with knee swelling/pain
Comment on this post
By Shelly
January 21, 2014
Shelly wrote
I was orig put on hydrocortisone, my joints all went bad, I had confused brain and memory loss. Then they put me on prednisolone, god I was in a rage all the time. At the end of 3 weeks my brain felt like it was going to burst. I'm being told I need steroids to live. But since I've taken them I'm just egsisting. I have trouble walking, my feet are so painful and my brain is mush.
Willow  |  March 30, 2014
I was put prednisone for wheezing. I am 46. On day 4. My heart
Rate is going down to as low as 52. I have dry mouth and
I'm talking more than normal. I have anxiety normally
And I'm freaking out about my heart rate. I can't confirm that its the
Prednisone but my heart rate is typically fast.
I am afraid my heart is going to just stop.
Marnie46  |  March 29, 2014
Prednisone had a similar effect on me. I became a lot more violent and easily irritated. I found that normal things would set me off and make me rageful. My mood was almost bipolar. It does go away once off the med for about a week or so. The mental changes are not permanent at all, but they are definitely the result of Prednisone.
March 24, 2014
Yes, definitely. This has happened to me as well as my sister, especially when the steroid (prednisone) levels are high. Talking more like if your really have too much caffeine in your system, also constant urination (more at night) and lastly sudden changes in mood.
Mark  |  March 12, 2014
YES! I am in the VERY same boat with my dad! I wish I had seen your post sooner.
mickilynn  |  February 22, 2014
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By Lighthouse
January 20, 2014
Lighthouse wrote
Prednisone and Suicidal
i was on prednisone 40mg i feel awful and low mood , cry every day i want kill myself not worth my life i hate steriod affect my heart fast beat and ectopic beat terrible but steriod reduce 5mg start feel better
yvonne  |  April 15, 2014
I was on 80 mg a day at the peak and it made me quite angry and violent. I was never near suicide but it definitely messed with my mind. However, I found that this effect ended about a week after I stopped taking it, and I did not have any serious withdrawal problems.
March 24, 2014
Yes, "speedy and talkative" is a common effect. The psychotic effects can kick in on higher doses. My husband was on 160 when he became psychotic the first time and 90 the second. What is important is that depression can occur while coming off, even tapering the correct way. Doctors know about that. What they need to also know is how to treat those who do show extreme lability. What you can do is make sure your doctors are aware.
Lighthouse  |  January 23, 2014
I'm so sorry to hear about your experience. I am wondering if my mom will get like that when she stops the prednisone. While on it, she is speedy and talkative and child-like acting. I'm wondering if it will be like a crash effect when it gets out of her system. Was your husband ever speedy and talkative on it?
shelly  |  January 21, 2014
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By CareBear2000
January 15, 2014
CareBear2000 wrote
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By may
January 14, 2014
may wrote
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By Tracy
November 17, 2013
Tracy wrote
On Prednisolone
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By Jean
November 7, 2013
Jean wrote
trunkel obesity caused by prednisone
I am currently in Anatomy and Physiology II at Northwest Florida State College and it sounds like you might have Cushing's Disease. General signs and symptoms of this includes fat redistribution (Truncal Obesity) and weight gain. However, it is treatable because all it is, is an overproduction of the hormone Cortisol. With that being said, just tell your family physician that you need a lab for your Cortisol/Corticosterone levels. Hope this helps!!
Malcolm Griffith  |  April 11, 2014
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September 19, 2013
JADE wrote
ulcer colitis and prednisone
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By Beveerly Johnson
September 19, 2013
Beveerly Johnson wrote
Trunkel obesity caused by prednisone
yes taking too much prednisolone can raise your cortisol levels causing obesity ie, cushings disease and un fortunately the only way to get rid of it is exercise, and also metabolic tests to check insulin levels hopes this helps
marie  |  December 3, 2013
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By Mockingbird813
September 2, 2013
Mockingbird813 wrote
Risperdal flat affect
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What patients are saying about Naproxen vs. Prednisone

976 patient discussions from healthcare websites and blogs
to taper the pred and am down to one naproxen. next is the...
...are to be able to completely prevent permanent damage. Even on NSD, I still have morning stiffness and soreness, especially in my thoracic and am still on the drugs in my sig. Which will Also cau...
from that to naproxen right before I started prednisone
...said are fine with prednisone. I just upped my pred to 15 so that ...Not sure Bout meloxicam and pred because I switched from that to naproxen right before I started predni...
it is more than i can take in the morn. i take a naproxen...
...up it due to pain, but i stubbornly want off the pred.  when it is more than i can take in the morn. i take a naproxen, which seems to help the ...and i always feel better after, although starti...
Next week I'm supposed to go to 5 mg of prednisone...
...(7.5 mg per day now, awesome considering I started at 60 mg 7 months ago) and switching to Lotemax at only 3 times per day. I'm still on 1000 mg of Naproxen. Next week I'm supposed to go...
has started to lose weight, her doctor changed to celebrex...
...20 mg MTX 2.5 mg prednisone folic acid and 100mg celebrex (we were on naproxen, but since she has started to lose weight, her doctor changed to celebrex last month). I don't...
and then added MTX orally, now changed to MTX injections,...
...once he was on Prednisone Naproxen and then added MTX orally, now changed to MTX injections, but he still has an active disease. His systemic features have gone (temperature, skin rash etc), but...
and just changed from Meloxicam to Naproxen due to liver...
...Naproxen due to liver problems. All these meds are used in RA, Lupus, Sjogren's and Psoriatic Arthritis (these 4 are what my doctors are narrowing down my symptoms too). Boofy- I'm sorry to ...
naproxen then switched to Mobic, then added Plaquinil,...
...with the easiest stuff first to try to get the inflammation under control. naproxen then switched to Mobic, then added Plaquinil, then added sulfasalazine but had reaction to ...do the prednison...
another 5mg of pred to 20mg. I am going to take the naproxen...
...clearly says that the pred is working. Downside is ...Today I am going down another 5mg of pred to 20mg. I am going to take the naproxen to help reduce a ...my appearance with the pred so w...
can't get this udner control we will switch to methotrexate...
...naproxen, and added protonix for my tummy, but as I wait for this flare to die down, I can't help but get scared sometimes.   If you have the time, it would be extremely comforting to know if you'...