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Metformin vs. Phentermine for Weight Loss

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Metformin

Rx
/ 395,652 posts
Other Names: Glucophage   Glumetza   Glucophage XR   Fortamet   Metforming

Phentermine

Rx
/ 57,008 posts
Other Names: Adipex P   Duromine   Fastin
Rating:
Based on 395,652 patient discussions on healthcare websites and blogs
Learn more
Rating: 3 out of 5
Based on 57,008 patient discussions on healthcare websites and blogs
Learn more
Metformin (International Nonproprietary Name, pronounced , originally sold as Glucophage) is an oral antidiabetic drug in the biguanide class. It is the first-line treatment drug of choice for the treatment of diabetes mellitus type 2, in particu... Read more on Wikipedia
Phentermine, a contraction of "phenyl-Butyl number Nomenclatureamine", is an appetite suppressant of the phenethylamine class. It is an amphetamine like stimulant.It is approved as an appetite suppressant to help reduce weight in obese patients when use... Read more on Wikipedia
Concern level
Top 3 Concerns
Nausea
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Hypoglycemia
Diarrhea
Concern level
Top 3 Concerns
Dry Mouth
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Palpitations
Irritability
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See all concerns, alternative treatments and more
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Help people by sharing experiences you've had with Metformin or Phentermine - your story could impact others.
Treato My Voice
By metformin experimenter
August 2, 2014
metformin experimenter wrote
meformin & thyroid (TSH)
1184views
Comment on this post
By Hemm
July 11, 2014
Hemm wrote
Metformin
1044views
I also take Metformin 500mg and my A1c was also 6.1 and I was told I'm pre-diabetic.I need yo lose weight and I believe that will take care of the whole pill taking thing.I have changed my the way I eat.
MKeith  |  September 21, 2014
Comment on this post
By rnbventure
June 25, 2014
rnbventure wrote
Phentermine and chills
1084views
The same thing happens to me and I'm on 30mg. It's the second time I've taken them and I experienced sweats and chills the first time but much worse than now. I agree with the others, your body is probably still trying to get used to it, so it's probably best to try a lower dose
Olivia  |  October 7, 2014
Danielle is right. You probably are taking too much. I had the same issue at first and then cut back on my dose and things got much better. Your body will get used to the medication. I have had weight loss success but I do have to be very conscious of what is going on in my body so that I can confer with my doctor about the changes. We've been able to play around with the dosage and are still working to find the write combination. Are you in touch with your doctor?
Cassaundra  |  August 8, 2014
I forgot to mention that belviq has been approved by the FDA. They even have free samples but you have to get the prescription from your doctor. Go to their website and check it out. Good luck on your weight loss journey.
Danielle  |  August 1, 2014
I've been taking phentermine since 2006 off and on. It works really well for weightloss. You might want to half your pill and work your way up to a whole pill. If this is a new medication for you it's probably just your body reaction to these new chemicals in your body. Try taking it on an empty stomach and eating about 20 minutes afterwards. Please let me know how it works out.
Danielle  |  August 1, 2014
Comment on this post
By Karenbc
April 29, 2014
Karenbc wrote
Metformin and Aleve
1295views
I was taking two pills a day and had to stop because I was constantly hungry. Maybe you nee to cut back to one.
Stephanie  |  August 23, 2014
I have been taking Metformin for about 4 yrs now, and just the thought of swallowing the pill makes me wanna gag. I hate the taste of it on my tongue. I also take it while I eat... at least before my last bite, so that I know that it will go down. Another thing I noticed is, when I forget to take it for a day, I get gassy when I start it again. I thought it was just me.
misteek  |  July 22, 2014
I HAVE BEEN TAKING 500 MGS OF METFORUM A DAY FOR 10 YEARS. AT FIRST IT MADE ME SICK. VERY SICK TO MY STOMACH. BUT I STARTED EATING SOMETHING FIRST BEFORE I TOOK MY PILL. I FOUND THAT WAS THE THING TO DO. NOW I JUST TAKE IT AND I DONT ET SICK ANYMORE
ALICE  |  June 29, 2014
There is a time release Metformin which helped me with some reactions. Dr. almost didn't mention it though. Tammy
June 23, 2014
I have the runs all day. If I bend down 2 tie my shoe, underwear change. My stomach is upset all the time. I'm afraid to pass gas, I might shard myself.
Tee  |  June 17, 2014
My doctor prescribed 1000 mg Metformin twice a day. I took just the first evening and second day morning and evening. I had a total throw up the whole evening dinner and little lunch grapefruit. I stopped taking that. I just went back to my old pill Glyb/Metformin 2.5/500. I watch what I eat now in order to take just half of it once daily. If I have a big dinner, I had to take the whole pill. I try to eat less meats and more vegetables. My sis just warned me on the long taking Metformin
Oli  |  June 17, 2014
I am light headed on the Metformin too. Just started it a couple of weeks ago.
JohnMc  |  May 26, 2014
Comment on this post
By Tony Botchagaloop
April 16, 2014
Tony Botchagaloop wrote
Phentermine and anemia
Comment on this post
By TJ.Jean
April 16, 2014
TJ.Jean wrote
Phentermine (discontinued after only 3 days)
2056views
Most likely in both cases here- you are having an allergic reaction. Did you contact your doctor about the severe side effects you were having? I've been on phentermine and what people have to be careful of is consuming alcohol with it, because it can lead to a very unpleasant blackout. I too suffer from anxiety and phentermine exacerbates those feelings because it stimulates the central nervous system. Everyone reacts to it differently and usually within 6-8 weeks a tolerance is developed and
July 26, 2014
Wow,the red face, severe hot flashes. I have them both, AND my liver enzymes went sky high. I have been taking it for months,,so now to slowly (they say not to stop abruptly) get off of phentermine. It seems like everything bad,points to this medicine.
sandra siguaw  |  June 29, 2014
Comment on this post
By Kaleigh 25 Yr. Old Female in Baltimore, MD
February 5, 2014
Kaleigh 25 Yr. Old Female in Baltimore, MD wrote
Taking Tramadol & Phentermine Together
4210views
The MD knew withdrawals are going to be expected. I was given chlonodine and phentermine to help. It worked will and now I am off meds. All this tx was supported by studies. A general MD will not have the knowledge to feel comfortable.
Rudy  |  May 31, 2014
Try to find a MD who is a pain management specialist along with being an addiction specialist or addictionologist. These doctors are much more knowledgeable on pain management along with other treatment that will help support your pain management. For example, my pain management MD had me on a pain med from a chronic injury. He also discovered I needed testosterone. After a year of treatment my chronic pain was feeling so much better that we decided to try to stop the pain meds. The MD kne
Rudy  |  May 31, 2014
It works like a miracle pill for me...almost at my weight lose goal...
cynthia  |  May 20, 2014
It made me hungrier too..dr took me off it cause I would gain and lose..looking in to something diff.
I' m bernita  |  April 30, 2014
does the phentermine work for you? seems to make me hungrier
jennifer  |  April 8, 2014
So how did your doctors appt go?
Chavez  |  March 12, 2014
Comment on this post
By Angel's Mom
January 23, 2014
Angel's Mom wrote
Metformin & Bad Breath
1569views
People with Chronic halitosis have no idea of how bad it is, when it is “on” or “off” and when it is really acutely tragic. Once the source is identified, a reasonable person will take every necessary action they know to do to remedy it or reduce it to a bearable level by all means necessary. I am a reasonable man, but unfortunately, i could not solve a problem i don't know how to fix.
I had suffered with it for over 5 years (correlating to my time on Metformin) and never knew the height, dept
DrMike76  |  August 13, 2014
Comment on this post
By zorine grimstead
January 3, 2014
zorine grimstead wrote
PHENTERMINE
1297views
Comment on this post
By Bre
December 10, 2013
Bre wrote
Phentermine experience
2282views
You may feel like to begin with, but watch what you eat. I am not craving squash and zucchini with chicken. I lost 20 pounds in just over 2 months taking phentermine and all I did was change what I ate. No diet, just changed eating habits. Drinks lots and lots of water, it helps tremendously!! Good luck!!
Melody  |  June 26, 2014
I just started phentermine but find myself hungrier on it then before I started taking it
April 8, 2014
Comment on this post
By Bob
December 5, 2013
Bob wrote
Type 2 Diabetes, Metformin and Lovastatin
1564views
That is interesting. Please keep posted as I am border line high cholesterol and they have debated wether they should risk cholestorol meds because I have a fatty liver, and it is a med that works throught the liver.
Nissa  |  January 10, 2014
Comment on this post
By stank mouth
October 15, 2013
stank mouth wrote
stanky mouth from metformin
1181views
Comment on this post
By Codierachel
September 30, 2013
Codierachel wrote
Phentermine & missed period
1132views
I started phentermine almost 2 months ago... I had a baby in march, and I am pretty sure my tubes were tied, but I am now 13-18 days late for my period. I know the chances of getting prego are slim when your tubes get tied but I am having all the symptoms and a freaked out to take a test.
August 11, 2014
You think?
uh  |  April 19, 2014
Comment on this post
By donna dube
August 21, 2013
donna dube wrote
metformin and stomach problems
1654views
You are supposed to take Metformin with food it does nothing but cause stomach issues if you don't.
Scott  |  November 18, 2014
i take metformin also.i have these weird like hunger pains to the point where im in severe pain i have looked up everything my thyroid and other stuff i just dont know what to do i hurt so bad
Nancy Mosley  |  September 22, 2014
I had the exact same problem - my consultant advised me to take 1500 metformin at bedtime which worked brilliant I don't suffer in the day anymore!! Best advise find a brilliant endocrine professor!! After five wrong diagnosis from different doctors I found a brilliant endocrine specialist he is a researcher and he has patients from all over uk! I have other endocrine problems thyroid etc and if it wasn't for him I'd have been palmed off with painkillers by other doctors that were clearly not
Andrea  |  September 1, 2014
Correction..... Taken
Carolyn  |  April 10, 2014
I know the feeling. It gave me lactic acidosis. I am trying to be compensated by the doctors who prescribed it without considering that I had chf and kidney damage. I was t Ken off the drug but two weeks later I am still dealing the gas, bloating. A gastroenterology is who studies the digestive tract

Carolyn  |  April 10, 2014
Comment on this post
By taneisa
August 16, 2013
taneisa wrote
fever blister from phentermine 30mg
Just a thought, because I too get cold sores - maybe you aren't drinking enough water so your lips got too dry, which could cause a cold sore. So indirect relation? or coincidence?
Ang  |  October 9, 2014
This isn't from phentermine specifically - but if you are prone to cold sores, stress can bring them on. And, if you were having anxious feelings, this could feel stressful. I get them, but haven't noticed any "sudden" eruptions or change in the occurrence since being on phentermine.
Michelle  |  July 21, 2014
That isn't from the phentermine. Dr. Meletio
June 7, 2014
Comment on this post

What patients are saying about Metformin vs. Phentermine

448 patient discussions from healthcare websites and blogs
results so far. When you have PCOS and metabolic syndrome...
...my PCOS, Metabolic Syndrome, and infertility with Metformin and Spironlactone ...am taking the phentermine and having good results so far. When you have PCOS and metabolic syndrome it is good...
Phentermine with Metformin. Started taking phentermine...
...to the doctor a couple of days ago, and he said there is no problem in taking Phentermine with Metformin. Started taking phentermine a couple of ...yourself when on phentermine, even though you...
pre-diabetic and he takes Metformin and it has really helped...
...pre-diabetic and he takes Metformin and it has really helped him a lot. He also takes phentermine and that has helped him ...strong as say Adderall which many children take, and it seems to me t...
get better i started mine 11 months ago an was so nauseous...
...to get use to metformin but it does get better i started mine 11 months ago an was so nauseous the first couple of ...after awhile my doctor prescribed phentermine to help with weight loss and i...
metformin for insulin resistance I had horrible side effects...
...I just started Phentermine today. It is weirdest feeling. But I feel like it is going to work. After my doctor prescribed my metformin for insulin resistance I had horrible side effects, so he took...
DIFFICULT WITH EVERYONE BUT THAT WAS THE WORST STOMACH PAIN...
...THE METAFORMIN AND IT WAS HORRIBLE!!! I KNOW THE EXPERIENCE MAY BE DIFFICULT WITH EVERYONE BUT THAT WAS THE WORST STOMACH PAIN I ...TO STOP TAKING THE PHENTERMINE BECAUS...
Have you ever been on Metformin and tried Phentermine for...
...you ever been on Metformin and tried Phentermine for weight loss? Did it work? An...
I've been taking it and haven't experienced any side effects...
...even though I had changed my diet and I exercise I still couldn't lose weight. I also take metformin. My question is: has anyone had any actual success with this? I've been taking it and haven'...
and it really makes a difference for me. However,...
I have taken phentermine with metformin and it really makes a difference for me. However, you need to be monitored very closely ...pressure changes if you take phentermine. Also, it is very impor...
So 17lbs in 2 months total. I have not had any side effects...
...was taking it with metformin. That month (actually this month, cause i just completed the whole month on both) I lost 12lbs. So 17lbs in 2 months total. I have not had any side effects and my dr sa...
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