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Glucotrol XL vs. Metformin for Type 2 Diabetes

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Glucotrol XL

Rx
/ 442 posts
Other Names: Glucotrol   Glipizide

Metformin

Rx
/ 383,033 posts
Other Names: Glucophage   Glumetza   Glucophage XR   Fortamet   Metforming
Rating:
Based on 442 patient discussions on healthcare websites and blogs
Learn more
Rating: 4 out of 5
Based on 383,033 patient discussions on healthcare websites and blogs
Learn more
Glipizide is an oral medium-to-long acting anti-diabetic drug from the sulfonylurea class. It is classified as a second generation sulfonylurea, which means that it undergoes enterohepatic circulation. The structure on the R2 group is a much larger cyclo... Read more on Wikipedia
Metformin (International Nonproprietary Name, pronounced , originally sold as Glucophage) is an oral antidiabetic drug in the biguanide class. It is the first-line treatment drug of choice for the treatment of diabetes mellitus type 2, in particu... Read more on Wikipedia
Concern level
Top 3 Concerns
Hypoglycemia
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Weight Loss
Weight Gain
Concern level
Top 3 Concerns
Nausea
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Hypoglycemia
Diarrhea
See all concerns, alternative treatments and more
See all concerns, alternative treatments and more
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Help people by sharing experiences you've had with Glucotrol XL or Metformin - your story could impact others.
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By metformin experimenter
August 2, 2014
metformin experimenter wrote
meformin & thyroid (TSH)
Comment on this post
By Hemm
July 11, 2014
Hemm wrote
Metformin
Comment on this post
By Karenbc
April 29, 2014
Karenbc wrote
Metformin and Aleve
I was taking two pills a day and had to stop because I was constantly hungry. Maybe you nee to cut back to one.
Stephanie  |  August 23, 2014
I have been taking Metformin for about 4 yrs now, and just the thought of swallowing the pill makes me wanna gag. I hate the taste of it on my tongue. I also take it while I eat... at least before my last bite, so that I know that it will go down. Another thing I noticed is, when I forget to take it for a day, I get gassy when I start it again. I thought it was just me.
misteek  |  July 22, 2014
I HAVE BEEN TAKING 500 MGS OF METFORUM A DAY FOR 10 YEARS. AT FIRST IT MADE ME SICK. VERY SICK TO MY STOMACH. BUT I STARTED EATING SOMETHING FIRST BEFORE I TOOK MY PILL. I FOUND THAT WAS THE THING TO DO. NOW I JUST TAKE IT AND I DONT ET SICK ANYMORE
ALICE  |  June 29, 2014
There is a time release Metformin which helped me with some reactions. Dr. almost didn't mention it though. Tammy
June 23, 2014
I have the runs all day. If I bend down 2 tie my shoe, underwear change. My stomach is upset all the time. I'm afraid to pass gas, I might shard myself.
Tee  |  June 17, 2014
My doctor prescribed 1000 mg Metformin twice a day. I took just the first evening and second day morning and evening. I had a total throw up the whole evening dinner and little lunch grapefruit. I stopped taking that. I just went back to my old pill Glyb/Metformin 2.5/500. I watch what I eat now in order to take just half of it once daily. If I have a big dinner, I had to take the whole pill. I try to eat less meats and more vegetables. My sis just warned me on the long taking Metformin
Oli  |  June 17, 2014
I am light headed on the Metformin too. Just started it a couple of weeks ago.
JohnMc  |  May 26, 2014
Comment on this post
By Angel's Mom
January 23, 2014
Angel's Mom wrote
Metformin & Bad Breath
1242views
People with Chronic halitosis have no idea of how bad it is, when it is “on” or “off” and when it is really acutely tragic. Once the source is identified, a reasonable person will take every necessary action they know to do to remedy it or reduce it to a bearable level by all means necessary. I am a reasonable man, but unfortunately, i could not solve a problem i don't know how to fix.
I had suffered with it for over 5 years (correlating to my time on Metformin) and never knew the height, dept
DrMike76  |  August 13, 2014
Comment on this post
By Bob
December 5, 2013
Bob wrote
Type 2 Diabetes, Metformin and Lovastatin
1273views
That is interesting. Please keep posted as I am border line high cholesterol and they have debated wether they should risk cholestorol meds because I have a fatty liver, and it is a med that works throught the liver.
Nissa  |  January 10, 2014
Comment on this post
By stank mouth
October 15, 2013
stank mouth wrote
stanky mouth from metformin
Comment on this post
By donna dube
August 21, 2013
donna dube wrote
metformin and stomach problems
1300views
I had the exact same problem - my consultant advised me to take 1500 metformin at bedtime which worked brilliant I don't suffer in the day anymore!! Best advise find a brilliant endocrine professor!! After five wrong diagnosis from different doctors I found a brilliant endocrine specialist he is a researcher and he has patients from all over uk! I have other endocrine problems thyroid etc and if it wasn't for him I'd have been palmed off with painkillers by other doctors that were clearly not
Andrea  |  September 1, 2014
Correction..... Taken
Carolyn  |  April 10, 2014
I know the feeling. It gave me lactic acidosis. I am trying to be compensated by the doctors who prescribed it without considering that I had chf and kidney damage. I was t Ken off the drug but two weeks later I am still dealing the gas, bloating. A gastroenterology is who studies the digestive tract

Carolyn  |  April 10, 2014
Comment on this post

What patients are saying about Glucotrol XL + Metformin + Type 2 Diabetes

9 patient discussions from healthcare websites and blogs
ago I was taking 1000 mg Metformin, 10-12 units of Lantus...
...week ago I was taking 1000 mg Metformin, 10-12 units of Lantus insulin and 5 mg Glucotrol XL. My A1C was at 6.3 ...doctor had me drop the Glucotrol XL and start taking Januvia. I've always had p...
put me on metformin. That worked well alone until last year...
...in October of 2000. I was first put on Glucotrol XL (glipizide) and was able to ...7.1, so the doc put me on metformin. That worked well alone until ...I'm 1000mg/2x a day metformin and 5mg o...
glipizide XL. I also take Metformin. But as of 4 days...
...started with 2.5 mg of Glucotrol XL, then 5 mg, then 2.5 ...glipizide XL. I also take Metformin. But as of 4 days ...all because the MD switched me over to Byetta. My first day without...
also use to be on metformin, glucotrol XL, and avandia for...
...also use to be on metformin, glucotrol XL, and avandia for my...
T2 I was placed on Glucotrol XL (glipizide). Six months...
...T2 I was placed on Glucotrol XL (glipizide). Six months ...numbers enough to switch me to Glucophage XR (extended release metformin). That dose was cut ...I changed my diet, lost weight, and ...
Currently I take 2000 mg metformin and 20 mg glucotrol...
...glucotrol xl. My numbers have been fair between 120 - 150. I started taking 200mg of Genemya, and Fenugeek daily with my normal meds. I have not changed anything. Still diet and exercise. But my nu...
  : diabetes, I started on glucotrol xl. I was having low...
...  : diabetes, I started on glucotrol xl. I was having low ...tried to take   : metformin/glucophage, and had too many ...extended release version? I had the gastro problems in spades, inclu...
insulin. I was doing good by taking Glucotrol XL and diet...
...blood sugar. You are on Metformin and it can take ...to be on insulin. I was doing good by taking Glucotrol XL and diet and exercise, but ...take pills as well. I am insulin resistant and nee...
of your questions. I'm on Metaformin 500mg 3x daily and...
To answer some of your questions. I'm on Metaformin 500mg 3x daily and Glucotrol XL 10mg 1x daily. I pretty much figured to stay away from HFCS, and I have been staying away from pretty much...
sooner than the metformin is taking effect? kaci
...terrorism. 1000 mg metformin and 5 mg of Glucotrol XL, water pill, 500 ...(1:00 a.m.) 1000 mg metformin, 2 hypertension meds, ...breakfast sooner than the metformin is taking effect? ka...
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