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Exemestane vs. Tamoxifen for Breast Cancer

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Exemestane

Rx
/ 12,496 posts
Other Names: Aromasin

Tamoxifen

Rx
/ 213,206 posts
Other Names: Nolvadex   Soltamox   Valodex
Rating: 2.5 out of 5
Based on 12,496 patient discussions on healthcare websites and blogs
Learn more
Rating: 4 out of 5
Based on 213,206 patient discussions on healthcare websites and blogs
Learn more
Exemestane (trade name Aromasin) is a drug used to treat breast cancer. It is a member of the class of drugs known as aromatase inhibitors. Some breast cancers require estrogen to grow. Those cancers have estrogen receptors (ERs), and are called ER... Read more on Wikipedia
Tamoxifen is an receptor antagonist of the estrogen receptor in breast tissue via its active metabolite, hydroxytamoxifen. In other tissues such as the endometrium, it behaves as an agonist, hence tamoxifen may be characterized as a mixed agonist/antagon... Read more on Wikipedia
Concern level
Top 3 Concerns
Joint Pain
Did you have
this too?
Suicidal
Weight Gain
Concern level
Top 3 Concerns
Hot Flashes
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this too?
Joint Pain
Blood Clots
See all concerns, alternative treatments and more
See all concerns, alternative treatments and more
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Help people by sharing experiences you've had with Exemestane or Tamoxifen - your story could impact others.
Treato My Voice
By Donna
June 30, 2014
Donna wrote
exemestane
I had stage three breast cancer. It is bilateral. I took Anastrozole for 8 months and was having miner muscle aches and fluid retention and well as sweats, weight gain. Switched to exemestane and every side effect listed I had. I only took it for 3 months. Went back to Anastrozole. I have been back on it for 3 months. I have muscle aches and cramps, fluid retention and miner hair loss. I will not take tamoxifin because of heart problems. When two years is up, I will discontinue taking any
TJ  |  November 12, 2014
Comment on this post
By Rosie
June 5, 2014
Rosie wrote
Dry mouth by Tampxifen
I feel like my mouth and throat are sticking together. I feel like there are rough dry spots that move around. ;-(
August 19, 2014
Yes I have the same dry mouth is very bad at night
Lib  |  August 5, 2014
I wake up at night so thirsty, I feel like I have been out in the desert. I chug down a bottle of water throughout the night. Now that causes me to have to run to the bathroom usually three times a night
July 19, 2014
I have dry mouth, too, mostly at night. Sometimes it gets so bad my mouth is almost glued shut.
Heather  |  July 18, 2014
I have it only at night, but its so bad that I have to keep gum or candy in my mouth. not every night, but most. It may be because I am not hydrating well enough during the day too.
July 15, 2014
I too have a very dry mouth and im finding eating more fruit watermelon is great it helps to quench the that incredible thirst too I hope that helps
liz  |  June 16, 2014
Comment on this post
By Ongoing ache left side of the back of my neck
May 14, 2014
Ongoing ache left side of the back of my neck wrote
Back Neck pain and tamoxifen
Comment on this post
By Millie
April 6, 2014
Millie wrote
Tamoxifen
Comment on this post
By janice
February 1, 2014
janice wrote
bleeding only just started tamoxifen
This happened to me 8 hours after taking first tamoxifen on 1st October. Has developef into full blown period. My last period was December 2013. Not sure if just coincidence.
Ann  |  October 3, 2014
Comment on this post
By Lindy
January 11, 2014
Lindy wrote
Tamoxifen
1237views
It's 5.00am in mid November 2014 and I stopped Tamoxifen in February 2014 and I still get burning hot at night - I must speak to my doctor WTF!
Cheryl  |  November 14, 2014
I too found myself nuts on tamoxifen with terrible anxiety. Finally found a drug that helped without interfering and it is busporine. It has saved me. I also opted for totally hysterectomy. That too has helped my craziness and anxiety. However the hot flashes are driving me crazy so I'm trying Peridin-c. Too soon to know if it will help with the sweats or not. But ask you doctor about Busporine for the anxiety.
Heidi  |  January 14, 2014
Comment on this post
By Beverly
October 7, 2013
Beverly wrote
Tamoxifen
1078views
Comment on this post
By Gretchen
October 5, 2013
Gretchen wrote
Night Sweats
Comment on this post
By KellyDen
August 11, 2013
KellyDen wrote
Neuropathy and Tamoxifen
1081views
Comment on this post

What patients are saying about Exemestane vs. Tamoxifen

1,366 patient discussions from healthcare websites and blogs
just over a week ago. I've had some nausea and headaches...
...from tamoxifen to exemestane just over a week ago. I've had some nausea and headaches (which I had when I started tamoxifen too) but that ...I have been horribly tired on tamoxifen so I...
joints and migraine headaches on Exemestane so was changed...
...had terrible aches in joints and migraine headaches on Exemestane so was changed back to Tamoxifen - do give it a goo...
exemestane. I experienced really bad aching joints so...
...I have just started taking tamoxifen after year of taking exemestane. I experienced really bad aching joints so oncologist suggested the change to tamoxifen. I will try anything but...
but hormone treatment didn't seem to work for me either....
I really hope Cap works for you. I tried Tamoxifen, Letrozole and Exemestane but hormone treatment didn't seem to work for me either. Cap is doing the trick at he moment so hopefully it will...
im taking exemestane. i was swapped from tamoxifen...
hello ellielou,.. im taking exemestane. i was swapped from tamoxifen because i suffered terrible side effects.. i was also ...2 months )and bad joint pain i had with tamoxifen have gone .. i do get...
However the exemestane did not work for me, but that is...
...after 2 years on tamox when I was 49. ...onc did was take me off tamox and on to ...away. However the exemestane did not work for me, but that is another story. So there may be no problem at ...
taking Exemestane for 5 years and have had no problems at...
...one group get Tamoxifen for 2.5 years ...to take part. I\\'m taking Exemestane for 5 years and have had no problems at all. My sister took Tamoxifen for 5 years and had huge problems so I was...
taking exemestane for 3 weeks with no side effects yet. The...
...recently been switched from tamoxifen to exemestane. I have been taking exemestane for 3 weeks with no side effects yet. The ...brands. Does anyone know if the same applies to exemestane? Is...
is a danger. It is far more tolerable for me than exemesta...
...effect, though I do have to watch my diet as weight gain is a danger. It is far more tolerable for me than exemestane which really made...
to Exemestane immediately and in August had my second bone...
...by ooperectomy last April. Switched from Tamoxifen to Exemestane immediately and in August had my second bone density scan. ...this. So I switched back to the Tamoxifen and the aromastase...
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