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Effexor vs. Topamax for Depression

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/ 207,097 posts
Other Names: Effexor XR   Venlafaxine


/ 100,988 posts
Other Names: Topiramate
Rating: 4 out of 5
Based on 207,097 patient discussions on healthcare websites and blogs
Learn more
Based on 100,988 patient discussions on healthcare websites and blogs
Learn more
Venlafaxine (brand name: Effexor or Efexor) is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class. First introduced by Wyeth in 1993, now marketed by Pfizer, it is licensed for the treatment of major depressive ... Read more on Wikipedia
Topiramate (brand name Topamax) is an anticonvulsant (antiepilepsy) drug. It was originally produced by Ortho-McNeil Neurologics and Noramco, Inc., both divisions of the Johnson & Johnson Corporation. This medication was discovered in 1979 by Bruce... Read more on Wikipedia
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Treato My Voice
By Stephanie
June 19, 2014
Stephanie wrote
OKAY SO I FINALLY FOUND SOMEONE WITH THE SAME PROBMEM AS ME. I'm 15 and a typically normal, healthy girl. Other than the fact that I get migranes every morning. So I was put on topamx for the migranes and it started out with me getting cramps and a sore back and then I was in the shower and it was almost like I was in a tunnel and everything slowly turned black and I passed out and fell. Luckily I didn't hit my head but it startled my mother. Then it happened again when I was doing my hair almo
January 12, 2015
I can not take Topirimat in 6/13 I had a brake through seizure on this med so I can only take the brand name.
Jessie  |  September 29, 2014
I take topiramate and get really bad periods, stomach pains all the time, and and really bad bone pain.
michelle  |  August 15, 2014
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By doodlebug
June 11, 2014
doodlebug wrote
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By 11111
June 1, 2014
11111 wrote
topamax hearing loss/rare side effects of topamax
Huh, My ears got all crazy too! I looked it up and it is a RARE side effect. So, I cut my dose as an experiment. Well, my ear is all better, but I take it for migraine prevention and now I had a migraine. So...doubling it back up...I wonder if an ENT could help?
Amanda  |  September 4, 2014
Topamax inflamed the glands, so that is what is happening in your ears. I had similar effect and even flue like symptoms. I cut down on the dosage and believing God to heal my body.
Sue  |  August 30, 2014
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By april
March 25, 2014
april wrote
Weigh the pros and cons
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By Amy
February 6, 2014
Amy wrote
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By Fabs
December 1, 2013
Fabs wrote
Cipralex vs Effexor
I was first treated with Cipralex, for Depression NOS, but it made me numb/depressed after 3 weeks. I eventually self-diagnosed with cylothymic disorder and my new pdoc has me on Effexor. It has almost instantly knocked out my ptsd. There are usually a couple days of exhaustion and restlessness when raising dosage. Despairing thoughts no longer frequent the mind. Course of treatment -1 year.
Spudz  |  July 5, 2014
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By dirk cunnington
September 10, 2013
dirk cunnington wrote
In praise of Effexor - wonder of wonders
This drug is horrible. It gave me a headache everyday for 6 weeks. I went off of it, and was extremely ill. I couldn't even get out of bed one of the days....sharp head pains, vomiting, diarrhea, nausea. DO NOT take this medication until you learn the withdrawal symptoms. Easing off of it slowly just prolongs the agony.
Sue  |  October 15, 2014
I concur wholeheartedly! "SO, don’t criticize Effexor because it didn’t give you what you were looking to get – embrace it because it takes you to a better place that you never knew existed. But you have to want to go there, to find your true self." Well said. By-the-by; I was recently rx'd a serotonin making drug called amyltriptaline- poof; brain favors it truly. Utopia might be some Mu receptors and Celebrex; then no unnecessary toil on my brain nor being nor spirit. Ah, but such is lif
dutchfish  |  June 13, 2014
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By Elizabeth
September 6, 2013
Elizabeth wrote
Effexor & Swollen Feet
How long did it take the swelling to go away? I'm experiencing this now after 2 weeks off of effexor 75mg. I decided I wanted my life back and stopped taking it. It's starting to hurt and I can barely stand for long periods of time. Please do respond and let me know if this gets better. I greatly appreciate it. email me at xxxx@xx.com if you could.
Rodney  |  January 19, 2015
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By judy
September 1, 2013
judy wrote
i have lost my mind completely
you are likely to have bpd ,,, Prozac. tegratol, and Haldol as needed worked miracles for my husband. First Prozac for 2 weeks and then add the tegretol don't know why the wait but it worked miracle like this,
monica  |  January 7, 2015
I was diagnosed with BPD and PTSD 22 years ago after a TBI. I've been on Effexor and Aderal since. I can't live without Effexor, it stabilizes my disregulated emotions but does nothing to stop the flashbacks. The only thing that I've found that will do that is Opium, which I don't want to go there, or some strains of canibis, which I do. I'm sill trying to find a pharma solution. My new research stream is that maybe adding Aricept might help. Anybody have any experience with that?
Chris  |  December 9, 2014
Does takeing covesyl lesson the effect of efexor
diane  |  August 26, 2014
wish you did too
August 20, 2014
I was on high dose effexor and also "lost" several years. I simply STOPPED taking this drug, and with the help/love/understanding of my wonderful lady, I have (so far) been able to function without it. For the first time in a long while, I am aware of what I am doing. It has been five LONG months, but..... I CAN DO IT!!
Russ  |  August 20, 2014
I can totally empathise with you I feel exactly the same - I am suffering from Anxiety & Depression have been taking venlafaxine and flupentixol for years and although I am much worse without the meds I still manage to embarrass myself on a regular basis to the point my eldest son is ashamed of me and doesn't care about me anymore. I worry constantly that the rest of my family will soon decide I am not good enough for them also and they will start to look down at me and decide to disown me, too
Diane  |  July 26, 2014
I understand what you are saying and how you feel. I think my son cares as well as a few other people but they are just tired of hearing it. I know I am and I'll bet you are too. I don't have any magic words. I wish I did.
Bonnie  |  March 27, 2014
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By Anna
August 30, 2013
Anna wrote
Increased weight, and memory problems
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What patients are saying about Effexor vs. Topamax

2,334 patient discussions from healthcare websites and blogs
on effexor and topomax and am unfortunatly suffering from...
...other depression and anxiety meds counteract painkillers? I am on effexor and topomax and am unfortunatly suffering from a undiagnosed ilness which causes severe pain. I was just put on oxycotin 20...
that was the Topamax . So far no problems. I have been on...
I was on Effexor and Trazadone. I gained a weight on Effexor. The Trazadone helped me ...taking my meds. I am on Topamax 200 mg. daily and ...and that was the Topamax . So far no problems. I ha...
and am now taking topamax, risperdal,and effexor and it...
...am now taking topamax, risperdal,and effexor and it is working beautifully. I do have some psychotic features to my mania but it has also helped with the anxiety and the suicidal thoughts. I can...
clinical depression and atypical bipolar. The Topamax helps...
...stabilization. I have clinical depression and atypical bipolar. The Topamax helps to augment the Effexor I take. I have almost no side effects. Higher ...I don't drink soda anyway, no groggines...
only after Topamax fails. Efexor works well apparently...
...you have ever considered using Efexor instead of Zoloft? Hain uses Efexor only after Topamax fails. Efexor ...side effects. And you might get by on a much lower dose too than what you're putting...
migraines I was on topamax and it worked great for me. I...
...for depression and had a bad reaction. For migraines I was on topamax and it worked great...
be a good substitute. Would topamax work better? Thank you...
...I taked effexor rx and want to switch to something else. The effexor has caused weight gain and hair loss. Do ...substitute. Would topamax work...
on 50mg of Topamax though and I don't have any side effects...
Effexor was causing me alot of problems too - especially gaining ...was on!! I'm only on 50mg of Topamax though and I don't have any...
I have found that the topomax has really helped stabilied...
...weight. On the topomax I do have memory loss, cognotive dulling, speech ...your doc. I am taking effexor with along with topomax. I have found that the topomax has really helped stabilied my moo...
topamax. One of the side effects of topamax is weight loss...
...by my DR. He made MAJOR med changes - he reduced the effexor by half, discontinued the risperdal, doubled my ...One of the side effects of topamax is...