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Cymbalta vs. Oxycodone for Pain

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Cymbalta

Rx
/ 150,553 posts
Other Names: Duloxetine

Oxycodone

Rx
/ 144,381 posts
Other Names: Oxycontin   Roxicodone   Oxyir   Oxynorm   Endone
Rating: 4.5 out of 5
Based on 150,553 patient discussions on healthcare websites and blogs
Learn more
Rating: 2 out of 5
Based on 144,381 patient discussions on healthcare websites and blogs
Learn more
Duloxetine (sold under the brand names Cymbalta, Ariclaim, Xeristar, Yentreve, Duzela) is a serotonin-norepinephrine reuptake inhibitor manufactured and marketed by Eli Lilly and Company. It is effective for major depressive... Read more on Wikipedia
Oxycodone (OxyContin and other brand names) is an opioid analgesic medication synthesized from opium-derived thebaine. It was developed in 1916 in Germany, as one of several new semi-synthetic opioids in an attempt to improve on the existing opioid... Read more on Wikipedia
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Help people by sharing experiences you've had with Cymbalta or Oxycodone - your story could impact others.
Treato My Voice
By Dennis
September 19, 2014
Dennis wrote
Oxycodne and my memory
Comment on this post
By irene
July 29, 2014
irene wrote
stealing
Thank you & I just been put on it by my doctor, a month now but, it's not helping my pain any!!!!
October 20, 2014
My wife was on oxycodone for years and ran into a lot of problems. She now takes Exalgo, a time released pill that she said works great and without all the side effects of oxy. She has chronic pain and says this works great. Get off the oxy. It's not easy to do but do it in steps. I also was on it and am now free of it
Got  |  August 18, 2014
Comment on this post
By Jackie
June 28, 2014
Jackie wrote
Cymbalta - Treatment for Crohn's Disease
Comment on this post
By char
June 27, 2014
char wrote
grand mal seizure and oxycodone
I have been taking oxycodone for about six years have had seizures before that the injuries form the seizures led to my having to take the oxy it does not usually cause them if they can't fine a reason for the seizure that is a good thing it is called idiopathic
flanimal1  |  September 21, 2014
Oxycodon will not cause seizures on its own when decreasing dosage or even when in full blown withrawel. You will feel like complete shit but unless there is an underlying health issue opiates/opioids are usually fairly safe to come off of. The addictive a substances that have dangerious withdrawels and can cause seizures if not properly tapered off are benzos (i.e. Xanax) and alchohol.
Lemon  |  July 25, 2014
Had you recently decreased your oxycodone dose (by even a small amount) or missed a dose (even if you didn't immediately feel any ill effects after the skipped dose)?
I had a seizure a few years ago after taking less of my xanax than usual for a couple days in a row. At first they couldn't find a cause for the episode, but ultimately chalked it up a change in the amount of xanax in my system. After years on high daily doses of xanax, my body took that as the norm and carried out its other funct
HH  |  July 4, 2014
Comment on this post
By softail
June 19, 2014
softail wrote
just learning up on some info.for my best friend thanks for being there ; )
Comment on this post
By Bobbie
March 27, 2014
Bobbie wrote
Carb Cravings on Cymbalta
Comment on this post
By GARY GERSIN
March 21, 2014
GARY GERSIN wrote
SEX
1666views
I have trouble reaching climax while on Lyrica. Also have major stomach/bowel issues when dose increased.
CountryCutie  |  October 16, 2014
Can't get an erection since starting Lyrica one year ago.
TomKat  |  July 28, 2014
well I am a lady and i find it hard, now to reach orgasm... its is frustrating and a lengthy process. I am on Lyrica 300 per day!
AllyKat  |  May 30, 2014
Comment on this post
By chiclets
March 18, 2014
chiclets wrote
Actavis generic vs. Teva generica (for Cymbalta)
Comment on this post
By RecallZydus
March 13, 2014
RecallZydus wrote
All Zydus generics
I am on 20 mg 4 times a day of Roxicodone. CVSis the pharmacy I always use n they give me the kvk brand up till this past month. I receive no pain relief from the brand Zydus. I also itchy as if I am elergic reaction n have to take Benadrial. I called Cvs and the told me this zydus brand is what there warehouse sends them. I then went to my doctors office and told his nurse the problem and her response was because of the FDA there was nothing they can do. So, I now am forced to lay in the bed h
Amanda  |  August 25, 2014
I just had the same experience with Zydus Labs 15 mg oxycodone. Panic, stomach issues, dilated pupils, heart palpitations. That's after only taking those for 3 days. I took them back to doctor, he wrote another prescription for the balance of unused meds. I called Zydus Labs and FDA, placed a adverse affect form with both. Now I have KVK brand, so much better.
T.B.  |  July 4, 2014
Comment on this post
By reid4keeps
February 19, 2014
reid4keeps wrote
Cymbalta and palpitations
Comment on this post
By Songstylist
January 31, 2014
Songstylist wrote
Cymbalta and Prestiq
Comment on this post
By captclap
December 7, 2013
captclap wrote
exalgo
Exalgo is very strong but it takes a few days to get up to full strength in the body. I take 2 oxycodone 10mg every 4 hours but after being prescribed exalgo 16mg I just take one in the morning and I'm good all day. Only need the oxy when break through pain gets tough.
Rob  |  February 17, 2014
16' rods??? wow, you must be an avatar creature to have 16 foot rods in your spine.
Rob  |  February 17, 2014
Comment on this post
By Deidre Ferrentino
November 3, 2013
Deidre Ferrentino wrote
Lortab 10/500
Comment on this post
By Krisathome
September 11, 2013
Krisathome wrote
Cymbalta and palpitations
Comment on this post
By trav
August 11, 2013
trav wrote
oxycodone/sleep apnea
I was on oxycodone for 6 yrs. went to work ,went to gym 5 A.M. Before work slept great . Best shape of my life after being hit by a snowplow and a TKR. Changed meds to oxycontin cant sleep ,cant work cant walk.?? MISERABLE ...
john  |  September 5, 2014
Although medicines affect everyone differently which is very true! If you Doctor orders a diagnostic test do not blow it off get it done you never know what could save your life. The most important thing is to have a great relationship with your Doctor and have one that you can trust and trusts you!!
Kevin  |  August 20, 2014
To Mary, sorry to hear about your story. It sounds like your daughter might have coincidentally developed a psychotic condition e.g. schizophrenia independently of the oxycodone. Not that I am a big fan of oxy, but if you get fixated on oxy as the cause of your daughter's psychosis, no one will take you seriously as opioids simply do not cause chronic psychosis (they can cause acute delirium). Hope things get better for you and your daughter.
Dave  |  June 24, 2014
It would be nice to have some kind of warning about comment length. Over half my last comment got cut off and lost, and nothing told me I had gone over any character limit. All that work, and pain, to type it out, and gone!
Jacob  |  April 23, 2014
That's right. All opioids can cause central sleep apnea, do to their respiratory depression effect. All meds of any kind can cause various adverse reactions in some people. But different people do react differently to different drugs. It's a matter of you and your doctor deciding if the benefits outweigh the risks.

Although opioids do tend to give me apnea, I need the pain control, and so I accept the adverse effects. I take morphine, with oxy for breakthrough, because the methadone I used t
Jacob  |  April 23, 2014
My daughter was on Oxy (presecribed by an incompetent GP) and after little over a year & Many pills later she became Psychotic from the meds. It was the only medicine she was taking & I watched the progression of the psychosis. I don't care what the drug companies Phony Reports say. Oxy Can Cause Psychosis---and it doesn't wear Off (even after the meds are stopped--we are over a year now!) and there Is No Cure. I hate the pharmaceutical companies they ruined my daughter's life--and her entire f
Mary  |  April 21, 2014
Also, I started out on 5 pain meds....down to just this one. And after being seen by a Maximized Living Chiropractor (beginning 11/2013) I have decreased the oxycodone by 30 pills a month - 3 months ago.
3 spinal fusions  |  April 8, 2014
I am 45, female and have been on oxycodone for 9 years and do not have sleep apnea. The sleep study verified that. sorry, but meds don't have the same effect on everyone.
3 spinal fusions  |  April 8, 2014
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What patients are saying about Cymbalta vs. Oxycodone

959 patient discussions from healthcare websites and blogs
a lot. I am taking oxycodone now and it helps a lot more....
You have taken Norco? I was on Norco and it helped but not a lot. I am taking oxycodone now and it helps a lot more. Just ...the anti depressants, I have heard Cymbalta works well. It is hard t...
oxycodone 2x day 2 weeks ago.Doesn't always work...did at...
...on 5 mg. oxycodone 2x day 2 weeks ago.Doesn't always work...did at first. ...and taking 800 motrin in ...pain control. I tried cymbalta with this and could not tolerate it. Anyone take...
I took Cymbalta for pain. It did not work (that could just...
My first post on BL: I took Cymbalta for pain. It did not work (that could just be in comparison with the oxycodone I was also taking). It did not improve my mood noticeably (that could also be in...
and Oxycodone and that combination works well. Your PM...
...taken upwards of 600mg of Lyrica a day after Gabapentin. I use the Lyrica with 60 mg of Cymbalta and the two work well for neuropathy. ...on Lyrica and Oxycodone and that combination works well...
Cymbalta 30mg has been a life saver for me just for...
...I've also had problems with Oxycodone. Some people are just ...with better results than Oxycodone. I am one of ...get a bit tricky. Cymbalta 30mg has been a life saver for me just for the ...
and/or Effexor. I am on Cymbalta 30mg and take Oxycodone...
...high dose of Oxycodone and/or Effexor. I am on Cymbalta 30mg and take Oxycodone for pain (no more than 40mg a day) and I don't have any...
Oxycodone 5/325 my life improved remarkably. My depression...
...have major depression and rhumetoid arthirtis. ...personality. When I switch to Cymbalta 60MG plus Oxycodone 5/325 my life improved remarkably. My depression is mostly gone and my pain from RA...
I had the same experience when I used to take Cymbalta
...and Oxycodone for pain. I experience both analgesia and euphoria without ...when I used to take...
u take oxycodone? try that. a good antidepressent...
...u take oxycodone? try that. a good antidepressent that i've tried is Cymbalta. It's the only ...in the am for some additional pep. cymbalta also helps with additi...
was able to get rid of the Mscontin and now am on Oxycodone
I take 60mg of Cymbalta daily. It has helped my depression greatly. Once I was put up ...days. It does decrease my pain level, But I still ...the Mscontin and now am on Oxycod...
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