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I have lymphedema in my legs. Nothing that was done to me medically helped reduce the swelling including diuretics. In an unrelated issue, I needed a steroid injection in my shoulder in January. I noticed that the swelling in my legs decreased overnight. Not a great deal but noticeable. The swelling stayed down for a few days but returned in a week or so. In that period I asked different doctors if the steroids could have done that. The answer was almost universally "no" except for my primary care doc who said it was possible - no more than that - just "possible."
In April I was hospitalized for a heart attack and pneumonia and I was given predizone while I was in the hospital for 4 days. During those 4 days, I lost 30 pounds and with it the swelling in my legs. I attributed the loss of fluid to the steroids since it was my second example of swelling going down after steroid therapy.
Again - nobody accepted that conclusion and simply said that steroids have the opposite effect and cause you to gain weight. The weight stayed off for about 5 months and now has come back along with the swelling in my legs. I wear compression socks - knee high - but they don't seem to help much.
I wonder if anyone else with lymphedema has been helped with steroids.