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Baclofen vs. Tizanidine for Spasms

Change usage

Baclofen

Rx
/ 40,992 posts

Tizanidine

Rx
/ 3,558 posts
Other Names: Zanaflex
Rating: 2.5 out of 5
Based on 40,992 patient discussions on healthcare websites and blogs
Learn more
Rating: 2.5 out of 5
Based on 3,558 patient discussions on healthcare websites and blogs
Learn more
Baclofen (brand names Kemstro, Lioresal, and Gablofen) is a derivative of gamma-aminobutyric acid. It is primarily used to treat spasticity and is under investigation for the treatment of alcoholism.It is an agonist for the GABA B recep... Read more on Wikipedia
Tizanidine (trade names Zanaflex, Sirdalud) is a drug that is used as a muscle relaxant. It is a centrally acting 2 adrenergic agonist. It is used to treat the spasms, cramping, and tightness of muscles caused by medical problems such as mul... Read more on Wikipedia
Concern level
Top 3 Concerns
Withdrawal
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Addiction
Depression
Concern level
Top 3 Concerns
Drowsy
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Nausea
Insomnia
See all concerns, alternative treatments and more
See all concerns, alternative treatments and more
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Help people by sharing experiences you've had with Baclofen or Tizanidine - your story could impact others.
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By sami
March 1, 2014
sami wrote
tizanidine with worse depresion, stomach problems and NO sleepiness!
Comment on this post
By Melissa
November 5, 2013
Melissa wrote
Baclofen vs Flexeri
I started with Baclofen then started flexeril. I swear by baclofen as the BEST. I honestly can't say much about flex because I really haven't given it a chance but I hope it the Baclofen works as good for you as it did for me. Also, it curbed my desire for the opiate pain relievers. My doc seems to want me stuck on them lol she took away the baclofen and gave me a shit load of tramadol and flexeril. Could be blissful if only I were ignorant..
Quamie  |  March 7, 2014
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What patients are saying about Baclofen vs. Tizanidine

782 patient discussions from healthcare websites and blogs
dantroline, and tizanidine before my baclofen pump. I ended...
...baclofen pump. I ended up getting drunk faster but it might have been due to the fact that i hadnt drank in a while due to my injury. Now i put them back like the good ol days i just have to watch ...
just swapped from Baclofen to Tizanidine but that's more...
...in my hands sometimes.  I've just swapped from Baclofen to Tizanidine but that's more for walking, the spasticity doesn't really interrupt my sleep. So maybe ask about amitriptyline or...
Baclofen weakened my legs so changed to tizanidine, they...
...weakened my legs so changed to tizanidine, they made me tired, ...and evening and baclofen midday. Just struggled round supermaarket hanging onto trolley. Get weird dreams with tizanidine - no...
I think the problems are a result of stopping the baclofen...
...for the replies, I dropped the baclofen last night and took 2mg of tizanidine It knocked me ...wake up with terrible insomnia, I think the problems are a result of stopping the baclofen, so I wi...
baclofen I was switched to Tizanidine which really works. ...
...was switched to Tizanidine which really works.  If i take 2 or 3 in the morning it knocks me out.  oddly though, I wake and feel incredible.  I am on all the typical spinal meds.  Good luck with...
has changed my meds to 100 mg baclofen, 16mg tizanidine,900...
...My dr has changed my meds to 100 mg baclofen, 16mg tizanidine,900 mg ...now. Do you thin increased exercise and possibly securing a standing frame would help to control these spasms and...
off baclofen and/or switching to tizanidine (e.g.) instead...
...if I were you, I would go and see my GP. It might be worth coming off baclofen and/or switching to tizanidine (e.g.) instead to see if it's the baclofen or not.   Kare...
to change me from baclofen to tizanidine as muscle weakness...
Tizanidine any one on it? Hi, ...decided to change me from baclofen to tizanidine as muscle weakness is getting to me. Anyone on tizanidine and any comments about it? Have to reduce baclofen...
pump. Just went from baclofen to tizanidine (sp?) and a...
...day for observation. I've discussed baclofen as well for spasticity and his opinion is some spasticity is good and as ...the pump. Just went from baclofen to tizanidine (sp?) and a prett...
just took me off baclofen and put me on Tizanidine, 2mg 2 x...
...took me off baclofen and put me on Tizanidine, 2mg 2 x daily, have been on it for a week and haven't had one cramp or felt dizzy as I did on Baclofen. I started...
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