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Avonex vs. Tecfidera (BG-12) for MS

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Avonex

Rx
/ 24,951 posts
Other Names: Rebif   Interferon Beta-1a

Tecfidera (BG-12)

Rx
/ 5,073 posts
Rating: 4 out of 5
Based on 24,951 patient discussions on healthcare websites and blogs
Learn more
Rating: 3.5 out of 5
Based on 5,073 patient discussions on healthcare websites and blogs
Learn more
Interferon beta-1a (also interferon beta-1-alpha) is a drug in the interferon family used to treat multiple sclerosis (MS). It is produced by mammalian cells while Interferon beta-1b is produced in modified E. coli. Interferons have been shown to h... Read more on Wikipedia
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Concern level
Top 3 Concerns
Flu Like Symptoms
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Headaches
Flu
Concern level
Top 3 Concerns
Progressive Multifocal Leukoencephalopathy
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Nausea
Itching
See all concerns, alternative treatments and more
See all concerns, alternative treatments and more
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Help people by sharing experiences you've had with Avonex or Tecfidera (BG-12) - your story could impact others.
Treato My Voice
By Leslie
July 24, 2014
Leslie wrote
Allergic reaction to Tecfidera
Comment on this post
By 2
June 11, 2014
2 wrote
My first week
One of the things that can be problematic is taking the Tecfidera while on an antibiotic. Tecfidera is an Immune suppressant So the antibiotics and and Tecfidera don't work together. Tecfidera slows down the immune system and antibiotics speed it up.
Ginger  |  July 18, 2014
Comment on this post
By Verna
May 3, 2014
Verna wrote
Tecfidera and weight loss
Comment on this post
By Myachinghead
January 16, 2014
Myachinghead wrote
Migraine
Comment on this post
By Martha Jones
December 30, 2013
Martha Jones wrote
Nanaforsame@yahoo.com
1031views
Comment on this post
By Vanessa
December 17, 2013
Vanessa wrote
Weight Loss
1597views
Loss of appetie almost immeadiatly. After 2.5 weeks, I need to set a timer to remember to eat.
JHS  |  June 25, 2014
I have been on Tec 2 weeks and am experimenting weight gain w/ hunger.
Lilly  |  April 4, 2014
I started on the tec November 2013, and started dropping a little weight consistently until I stopped it just 2 weeks ago. I would have stayed on it but for the other side effects- debilitating nausea, headaches, tooth and gum lesions and pain and hair loss. When I was asked by someone if I had cancer (because of the weight loss) that was enough for me. I should have known better than to consume cleaning products even if they have "reformulated" it and put it in a capsule. I'm getting tir
Cyndie  |  March 29, 2014
Why Tec? I see no weightloss info on it...
Ramprat  |  February 26, 2014
I've been on Tecfidera about four months now and have lost 20 pounds. While I walk miles and miles every day and eat really well, I haven't really changed diet or exercise.
Kristin  |  January 28, 2014
I've been on Tec for over 3 months now. I've lost about 15lbs w/o dieting or much exercise. Going to see the dr soon
SoccerDad  |  January 26, 2014
Comment on this post
By Linda
December 12, 2013
Linda wrote
Tecfidera
1283views
One of the things that can be problematic is taking the Tecfidera while on an antibiotic. Tecfidera is an Immune suppressant So the antibiotics and and Tecfidera don't work together. Tecfidera weakens the immune system and antibiotics strengthen the immune system.

I would highly advise that if you have any kind of infection and are about to start a regime of Tecfidera consult your doctor and do not start until you are infection free.
Ginger  |  July 18, 2014
I have been on Tecifedera for 8 months now and it has been a blessing. I have not had a flareup since on it whereas before it was everyother month. The flushing can be avoided by taking an aspirin with it...it really is a great medication! I recomend switching to it.
Megan  |  May 31, 2014
Comment on this post
By kay s
November 3, 2013
kay s wrote
Avonex made me extremely angry and almost violent
Comment on this post
By Marcia
September 5, 2013
Marcia wrote
Tecfidera
1497views
Pam I also am experiencing extreme fatigue. I am not sure if it's just my MS or if the drug is making it worse. I feel like my arms and legs have weights attached to them.
Ann  |  March 11, 2014
I recently switched from Copaxone, after 10 years. I had no injection sites left. I have been on Tecfidera about 7 months. My recent MRI scans is stable. I still flush, intermittently, several hours after meals. Benadryl handles it well. The major side effect that I have is extreme fatigue. This is different than my normal MS fatigue. I am trying to stick with it to see if after time, it subsides. Hope this helps!
Pam  |  January 6, 2014
Hi Marcia, I do not take Tecfidera but am considering it. I have taken copaxone for over ten yrs. now and have had some flares with optic neuritis, heavy legs with difficulty walking and some fat destruction in my legs where shots are done but Copaxone seems to be working and I feel very stable. I do try to stay out of the sun and to keep my stress as low as possible (read Bible for this every p.m.). I am looking into Tecfidera as I would like to stop taking shots daily. jane
jane  |  September 16, 2013
Comment on this post
By Cheryl Baker
August 22, 2013
Cheryl Baker wrote
I've been on Tecfidera for about 3 months...
2042views
It does get better, Trisha. For me it is an every once-in-a-while side effect. It only happens maybe once every 2-3 months.
Cheryl Baker  |  June 10, 2014
I just started low dose 120 mg Tecfedra. I'm just now 3d week getting the sweats.
I'm getting real horrible sweats ( flushing ). I haven't even begun the 240 mg dose &
I'm bout ready to throw in the towel. I'm so misrable. I haven't been able to stay on
anything, this was my really big hope! Does this constant heat go away? Feels like Im
A furnace on the inside. I get dripping wet. Just begun on third week too. I thought this time
I'd make it. Anyone else have this problem ?
Trisha  |  June 10, 2014
I've been on the Tecfidera for a month and now am having unusually heavy cycle that came 2weeks early.
Michelle  |  May 16, 2014
I have been on it for 6 months and have not had those issues.
Pam  |  January 6, 2014
Comment on this post
By IVY
August 9, 2013
IVY wrote
betaseron
Comment on this post

What patients are saying about Avonex vs. Tecfidera (BG-12)

407 patient discussions from healthcare websites and blogs
just started Tecfidera after four years on Avonex. The...
...have just started Tecfidera after four years on Avonex. The side effects of Avonex never let up. ...touch with anyone else who is taking Tecfidera. So ...
to what I'm reading, Tecfidera is much more effective
...started on Tecfidera. The flu symptoms of avonex had be in bed about 36 every week. I felt horrible. So far this seems to be much better. And according to what I'm reading, Tecfidera is much...
It would be amazing if drugs didn't have side effects...
...still believe Tecfidera provides the most long-term benefits and that is why I take it. It would be amazing if drugs didn't have side effects, but that ...you experience side effects on Avon...
very well on it and has had no relapses or bad side effects...
...in BG12, Since I have a friend who is in one of the trials in Australia. She has done very well on it and has had no relapses or bad side effects. I ...not doing better then the control drug A...
with the tecfidera stomach issues on ms world. Avonex...
...a 50% reduction in relapse rate. Avonex has around a ...about dealing with the tecfidera stomach issues on ms world. Avonex has flu like symptoms. When I was ...a week. The tecfidera is...
from Avonex to Tecfidera in May. I have had no issues...
I switched from Avonex to Tecfidera in May. I have had ...with this drug and feel better. You may want to look at the Tecfidera thread below for additional suggestions....
I've been on Tecfidera for about 4 months now,...
...now, having switched from Avonex, and I'm doing pretty well on it. I tolerated the initial titration dose really well and when bumped up to 240 mg twice a day did OK for a while. However, I...
posted they had been taking BG12 for about 2 years. They...
...they had been taking BG12 for about ...doing a trial. I just wanted to see what anyone who did the trial tesing, for BG 12, thinks about it ...but nervous. Been on Avonex but I really dont l...
Well...although I did not experience the usual side effects...
...I was on Avonex for 16 years, with very few symptoms. Last year, ...I changed to Tecfidera, when it was first available. Well...although I did not experience the usual side effects, I felt incre...
Well...although I did not experience the usual side effects...
...I was on Avonex for 16 years, with very few symptoms. Last year, ...I changed to Tecfidera, when it was first available. Well...although I did not experience the usual side effects, I felt incre...
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