Amitiza works great. Used it for a long time. The best combo that worked for me was amitiza once a day with bethenachol for bloating and cymbalta for pain blockage. My doctor was a miracle worked.
Linzess vs. Amitzia --- Linzess, hands down!
I took Amitzia for a couple of weeks and ALL I got was chronic GAS and anal leakage. Gross, I know. Why do you think I'm posting as "anonymous"?! I am talking, I couldn't stand myself! I was bound to my house because I was sure I'd get kicked out of any public facility I dared to enter. The bloating was horrible also. I NEVER had a bowel movement the entire two weeks I was taking amitzia. I was admitted to the hospital because they were concerned I had a blockage. No blockage, just severe constipation. I should add that I have sjogren's syndrome, so that is one cause of the chronic constipation I have suffered for YEARS. Then, my dr. prescribed Linzess. It changed my life!! I took 2 on the first day and within 2 hours, I had a bowel movement. I had several after that; not diarrhea, just really good bowel movements. I take one a day now and I am fairly regular. When I'm not, I take 2 at a time and get relief within hours. Linzess is AWESOME. No CRAZY flatulence fest. No anal leakage. No diarrhea. No bloating. Yay Linzess ;)
Linzess effectiveness and side effects
Bloating while on Linzess
Linzess- constipation IBS